AI Article Synopsis
- Pancreatic cancer is known for its aggressive nature and low survival rates, making research critical.
- Discovering microRNAs (miRNAs) has opened new avenues for understanding the disease, as they play significant roles in factors like cancer cell growth and resistance to treatment.
- This review highlights recent findings on how miRNAs affect pancreatic cancer and explores their possible applications in clinical settings.
Article Abstract
Pancreatic cancer (PC) is an aggressive malignancy with poor survival. The discovery of microRNAs (miRNAs) has provided a new opportunity to study the disease. Thus far, altered expression of miRNAs has been reported in a wide range of malignancies, including PC, and some miRNAs are associated with PC cell proliferation, invasion, chemoresistance, and patient survival. This review summarizes recent advances with respect to the roles and mechanisms of miRNAs in PC and discusses potential clinical applications.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275100 | PMC |
| http://dx.doi.org/10.1007/s00268-010-0952-z | DOI Listing |
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