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Influenza vaccine hesitancy and its determinants among Lebanese public transportation drivers.
Vaccine X
January 2025
Rafic Hariri School of Nursing, American University of Beirut, Beirut, Lebanon.
Introduction: According to the National Institute for Occupational Safety and Health, ensuring influenza vaccination for public transportation drivers is considered a public health objective, given that these drivers are at high risk of contracting influenza. The main purpose of this cross-sectional study is, thus, to evaluate influenza vaccine hesitancy (VH) and its determinants among a representative sample of Lebanese public transportation drivers.
Methods: A survey questionnaire is conducted between January and March 2023, with the participation of a proportionate purposeful sample of 509 drivers from various regions in Lebanon.
The impact of arbuscular mycorrhizal colonization on flooding response of .
Front Plant Sci
January 2025
Department of General and Applied Botany, Institute of Biology, Leipzig University, Leipzig, Germany.
Climate change is expected to lead to an increase in precipitation and flooding. Consequently, plants that are adapted to dry conditions have to adjust to frequent flooding periods. In this study, we investigate the flooding response of , a Mediterranean plant adapted to warm and dry conditions.
View Article and Find Full Text PDFMuscle-derived extracellular vesicles mediate crosstalk between skeletal muscle and other organs.
Front Physiol
January 2025
National Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing, China.
Skeletal muscle (SKM) has crucial roles in locomotor activity and posture within the body and also functions have been recognized as an actively secretory organ. Numerous bioactive molecules are secreted by SKM and transported by extracellular vesicles (EVs), a novel class of mediators of communication between cells and organs that contain various types of cargo molecules including lipids, proteins and nucleic acids. SKM-derived EVs (SKM-EVs) are intercellular communicators with significant roles in the crosstalk between SKM and other organs.
View Article and Find Full Text PDFSingle-cell profiling of SLC family transporters: uncovering the role of SLC7A1 in osteosarcoma.
J Transl Med
January 2025
Department of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
Background: Osteosarcoma is the most common malignant bone tumor in children and adolescents, characterized by high disability and mortality rates. Over the past three decades, therapeutic outcomes have plateaued, underscoring the critical need for innovative therapeutic targets. Solute carrier (SLC) family transporters have been implicated in the malignant progression of a variety of tumors, however, their specific role in osteosarcoma remains poorly understood.
View Article and Find Full Text PDFSLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer.
Sci Rep
January 2025
Nottingham Breast Cancer Research Centre, Academic Unit of Translational Medical Sciences, School of Medicine, University of Nottingham, University of Nottingham Biodiscovery Institute, University Park, Nottingham, NG7 2RD, England.
Cancer cells exhibit altered metabolism, often relying on glutamine (Gln) for growth. Breast cancer (BC) is a heterogeneous disease with varying clinical outcomes. We investigated the role of the amino acid transporter SLC1A5 (ASCT2) and its association with BC subtypes and patient outcomes.
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