The frequency of spontaneous and gamma-ray induced autosomal recessive lethals has been studied in chromosomes 2 and 3 at different stages of Drosophila melanogaster radiosensitive mutant rad (2) 201G1 oogenesis. The frequency of spontaneous lethals in radiosensitive mutant was higher by the order of magnitude as compared with wild-type flies (9.3 and 0.6%, respectively). Germ cells of radiosensitive mutant were of high mutability at all stages of oogenesis studied. The irradiation of flies by 1.29 x 10(-1) Kl/kg results in decrease of lethals frequency in radiosensitive mutant as compared with the spontaneous level, whereas under irradiation by 7.74 x 10(-2) Kl/kg no change in mutability was revealed.
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