Background And Objective: Treatment of oral lichen planus (OLP) remains a great challenge for clinicians. The aim of our study was to compare the effect of low intensity laser therapy (LILT) with topical corticosteroids in the treatment of oral erosive and atrophic lichen planus.
Materials And Methods: Thirty patients with erosive-atrophic OLP were randomly allocated into two groups. The experimental group consisted of patients treated with the 630 nm diode laser. The control group consisted of patients who used Dexamethason mouth wash. Response rate was defined based on changes in the appearance score and pain score (Visual Analogue Scale) of the lesions before and after each treatment.
Results: Appearance score, pain score, and lesion severity was reduced in both groups. No significant differences were found between the treatment groups regarding the response rate and relapse.
Conclusion: Our study demonstrated that LILT was as effective as topical corticosteroid therapy without any adverse effects and it may be considered as an alternative treatment for erosive-atrophic OLP in the future.
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http://dx.doi.org/10.1089/pho.2010.2876 | DOI Listing |
JMIR Res Protoc
January 2025
Department of Dermatology, Hospital Universitario Ramon y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain, Madrid, Spain.
Background: Psoriasis is an inflammatory disease primarily treated through molecular-targeted therapies. However, emerging evidence suggests that dietary interventions may also play a role in managing inflammation associated with this condition. The Mediterranean diet (MedDiet), prevalent in southern European countries, has been widely recognized for its ability to reduce cardiovascular mortality, largely due to its anti-inflammatory properties.
View Article and Find Full Text PDFSci Adv
January 2025
Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, Grudziadzka 5, 87-100 Torun, Poland.
Measuring low light absorption with combined uncertainty <1 per mil (‰) is crucial for many applications. Popular cavity ring-down spectroscopy can provide ultrahigh precision, below 0.01‰, but its accuracy is often worse than 5‰ due to inaccuracies in light intensity measurements.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Stanford University, Department of Mechanical Engineering, Stanford, California 94305, USA.
The extreme electric fields created in high-intensity laser-plasma interactions could generate energetic ions far more compactly than traditional accelerators. Despite this promise, laser-plasma accelerator experiments have been limited to maximum ion energies of ∼100 MeV/nucleon. The central challenge is the low charge-to-mass ratio of ions, which has precluded one of the most successful approaches used for electrons: laser wakefield acceleration.
View Article and Find Full Text PDFMol Neurobiol
January 2025
Center for Biomedical Engineering, School of Information Science and Technology, Fudan University, Shanghai, 200433, China.
Weightlessness usually causes disruption of the gut microbiota and impairs cognitive function. There is a close connection between gut microbiota and neurological diseases. Low-intensity pulsed ultrasound (LIPUS) has a beneficial effect on reducing intestinal inflammation.
View Article and Find Full Text PDFAnn N Y Acad Sci
January 2025
Environmental Physics Laboratory (EPhysLab), Centro de Investigación Mariña, Universidade de Vigo, Ourense, Spain.
This study uses a combination of the FLEXPART Lagrangian dispersion model with the Weather Research and Forecasting (WRF) mesoscale Eulerian model (FLEXPART-WRF) to analyze the expected mid- to late-century changes in the moisture sources and sinks of the North American East Coast (ENA) and the Gulf of Mexico (GM), as well as their most relevant abrupt moisture transport events-atmospheric rivers (ARs) and low-level jets of the Great Plains (GPLLJ) and the Caribbean (CLLJ). Both the ENA and GM are expected to increase in importance as moisture source regions over the century, both overall and in their contributions to the ARs and both LLJs. A notable increase in the intensity of the GPLLJ and CLLJ moisture sources is also observed.
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