AI Article Synopsis

  • Nontuberculous mycobacteria (NTM) were found in a study of 45,891 samples from patients initially diagnosed with pulmonary tuberculosis between 2004 and 2009.
  • Of the 10,041 culture-positive samples, only 208 were identified as MOTT, which is about 2.1% of the pulmonary samples.
  • Among the identified cases, the most common causative agents were M. avium complex, M. abscessus, and M. kansasii, highlighting the need for accurate diagnosis and treatment strategies for infections caused by these mycobacteria.

Article Abstract

Nontuberculous mycobacteria were identified from 45891 samples of 19553 patients with a prediagnosis of pulmonary tuberculosis between November 2004 and January 2009. Among 10041 (21.9%) culture positive samples, 208 (2.1%) pulmonary samples recovered from 77 individual patients were differentiated as mycobacteria other than tuberculosis (MOTT). Proportion of mycobacteria evaluated as causative agent for clinical infection were found as 0.16% (n = 31), mostly M. avium complex, M. abscessus and M. kansasii. Additionally, M. fortuitum-peregrinum complex, M. simiae, M. szulgai / intermedium and M. scrofulaceum were found as causative agent in 2, 2, 2 and 1 patient, respectively. Identification of infections caused by environmental or opportunistic pathogen mycobacteria is required in rapid and accurate diagnosis, infection control and treatment planning of infections caused by M. tuberculosis complex and/or MOTT.

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