The article deals with 140 cardiotocographic curves during opening and 147 curves during expulsion in puerpera in whom delivery was performed under cardiotocography and pH-metry. During different changes of foetal heart frequency pH values of foetal blood were determined. On the basis of cardiotocographic changes the examined group was divided into several subgroups. In each group the mean values of current pH were compared with the mean values of the control group. The control group consisted of 41 cardiotocographic curves during opening and 41 during expulsion in patients with normal delivery and clear foetal liquid. The pH of foetal blood was determined during opening and expulsion. Mean pH values of foetal blood were significantly lower during opening with expressed variable DIP-I and DIP-II as well as with slight and strong bradicardy. During expulsion a significant fall of mean pH values was observed only in the group with expressed variable DIP-I and DIP-II. Consequently the Apgar score of newborn infants was reduced. The mean pH values in other cardiotocographic changes were decreased but statistically insignificant. The same was observed in Apgar score.
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Front Pharmacol
January 2025
Department of Obstetrics, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, China.
Background: Gestational diabetes mellitus (GDM), a severe pregnancy disorder, is a temporary form of diabetes that occurs during gestation. Astragaloside IV (AS IV), a natural and effective composition of , shows pharmacological effects against diabetes. On the contrary, the effects of AS IV on GDM development are still not clear.
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Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran.
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January 2025
Department of Intensive Care Medicine, Army Medical Center of PLA, No. 10 Changjiang Road, Yuzhong District, Chongqing, 400010, People's Republic of China.
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View Article and Find Full Text PDFBMC Pregnancy Childbirth
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View Article and Find Full Text PDFNat Commun
January 2025
MOE Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin, 300350, China.
Embryonic and fetal development can be affected during gestation by exposure to xenobiotics that cross the placenta. Liquid crystal monomers (LCMs) are emerging contaminants commonly found in indoor environments; however, whether they can cross the placenta and affect placental development remains unexplored. Here, we develop an evaluation system that integrates human biomonitoring, uterine perfusion in pregnant rats, and placental cells.
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