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Atypical lymphoplasmacytic and immunoblastic proliferation: A Systematic Review.
J Clin Exp Hematop
June 2024
Department of Molecular Hematopathology, Okayama University Graduate School of Health Sciences, Okayama, Japan.
Article Synopsis
- Atypical lymphoplasmacytic and immunoblastic proliferation (ALPIBP) was first identified in 1984 in lymph nodes linked to autoimmune diseases but lacks a clear definition and understanding.
- A review of peer-reviewed literature revealed 55 cases of ALPIBP, predominantly affecting older women, with common diagnoses including rheumatoid arthritis, systemic lupus erythematosus, and autoimmune hemolytic anemia.
- There is a need for increased awareness of ALPIBP among pathologists and clinicians to prevent misdiagnosis and unnecessary treatments related to hematological malignancies.
Pulmonary and retroperitoneal lesions induced by methotrexate-associated lymphoproliferative disorder in a patient with rheumatoid arthritis.
Mod Rheumatol
December 2016
c Division of Respiratory Diseases, Department of Internal Medicine , Jikei University School of Medicine, Tokyo , Japan.
A 78-year-old man had fatigue and appetite loss for 5 months. He had been receiving low-dose methotrexate for rheumatoid arthritis. Computed tomography revealed multiple pulmonary infiltrations and muddiness of the fatty tissue surrounding the right kidney, ureter wall thickening, and hydroureter/nephrosis, which were suspected retroperitoneal fibrosis.
View Article and Find Full Text PDFMethotrexate-associated lymphoplasmacytic lymphoma complicated with type 2 cryoglobulinemia.
Int J Hematol
February 2011
Department of Hematology, Osaka Red Cross Hospital, 5-30 Fudegasaki, Ten-noji, Osaka, 543-8555, Japan.
Methotrexate-associated lymphoproliferative disorder in a patient with rheumatoid arthritis presenting in the skin.
J Am Acad Dermatol
April 2007
Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, USA.
A 91-year-old woman who had been taking methotrexate for approximately 5 years for rheumatoid arthritis developed papules and nodules on her face that enlarged during 6 months. A series of biopsy specimens demonstrated a lymphoplasmacytic infiltrate with increasingly atypical histopathologic features that resembled diffuse large B-cell lymphoma. Epstein-Barr virus was not identified.
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