A rare case of ergotamine-induced solitary rectal ulcer is described in a 41 year old woman who used high doses of ergotamine tartrate-containing suppositories for severe migraine headaches. Complete recovery of the ulcer was noticed after cessation of treatment with the suppositories. The relevant literature is discussed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2429605 | PMC |
| http://dx.doi.org/10.1136/pgmj.66.776.483 | DOI Listing |
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Ergotamine-induced solitary rectal ulcer.
Postgrad Med J
June 1990
Rusinow Department of Internal Medicine, Tel Hashomer, Israel.
A rare case of ergotamine-induced solitary rectal ulcer is described in a 41 year old woman who used high doses of ergotamine tartrate-containing suppositories for severe migraine headaches. Complete recovery of the ulcer was noticed after cessation of treatment with the suppositories. The relevant literature is discussed.
View Article and Find Full Text PDFAnorectal ulceration was observed in 6 patients who excessively used suppositories containing ergotamine tartrate. The mucosal lesions of the rectum resembled those observed in the "solitary rectal ulcer syndrome." However, characteristic features of ergotamine-induced ulcers are absence of a mucosal prolapse, lack of a history of constipation, and rapid healing after discontinuation of the drug.
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