3-Benzyl-2-(4-fluorophenyl)-1,3-thiazolidin-4-one.

Acta Crystallogr C

Ciudadela Universitaria, Universidad Tecnológica del Chocó, AA 292 Quibdo, Colombia.

Published: January 2011

The title compound, C(16)H(14)FNOS, crystallizes with Z' = 2 in the space group P2(1)/c. In one of the two independent molecules, the heterocyclic ring is effectively planar, but in the other molecule this ring adopts an envelope conformation. The molecules are weakly linked by two C-H···O hydrogen bonds to form C(2)(2)(14) chains. Comparisons are made with some symmetrically substituted 2-aryl-3-benzyl-1,3-thiazolidin-4-ones.

Download full-text PDF

Source
http://dx.doi.org/10.1107/S0108270110044550DOI Listing

Publication Analysis

Top Keywords

3-benzyl-2-4-fluorophenyl-13-thiazolidin-4-one title
4
title compound
4
compound c16h14fnos
4
c16h14fnos crystallizes
4
crystallizes space
4
space group
4
group p21/c
4
p21/c independent
4
independent molecules
4
molecules heterocyclic
4

Similar Publications

Original article: Efficacy and safety of single-dose suraxavir marboxil tablet in the treatment of acute uncomplicated influenza in adults: a multi-center, randomized, double-blind, placebo-controlled phase 2 clinical trial.

Clin Microbiol Infect

January 2025

National Center for Respiratory Medicine; State Key Laboratory of Respiratory Health and Multimorbidity; New Cornerstone Science Laboratory; National Clinical Research Center for Respiratory Diseases; Department of Respiratory Medicine, Capital Medical University, Institute of Respiratory Medicine of Capital Medical University; Chinese Academy of Medical Sciences; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China. Electronic address:

Objectives: To evaluate the therapeutic effect of suraxavir marboxil (GP681, abbreviated as suraxavir) in adults with uncomplicated influenza.

Methods: We conducted a multi-center randomized, double-blind, placebo-controlled phase 2 trial in 18 Chinese centers. Participants had to be aged 18-65 years with positive influenza test, presenting with at least one influenza systemic and respiratory symptoms in at least moderate severity within 48 hours of onset.

View Article and Find Full Text PDF

Polycystic ovarian syndrome (PCOS) is a low-grade and chronic inflammation defined by irregular hormonal status that primarily triggers females in their reproductive age. Multi cysts are a primary manifestation of PCOS; a high level of androgen production characterizes the condition via ovaries. Rheumatoid arthritis (RA) is a chronic, systemic, and symmetrical inflammatory autoimmune disease that affects 1-2% of adults.

View Article and Find Full Text PDF

Georgios Photeinos and his (1835) published in Ottoman Smyrna.

Pharmazie

December 2024

Department of the History of Pharmacy and Ethics, Erciyes University Faculty of Pharmacy, Kayseri, Turkey.

The , authored by Ottoman pharmacist Georgios Photeinos and published in 1835 in Smyrna (modern-day Izmir, T??rkiye), is a historically significant yet largely overlooked work in 19th-century pharmaceutical literature. At a time when modern pharmaceutical resources in Greek were scarce, Photeinos sought to address this gap by creating a comprehensive pharmacopoeia that extensively drew from the Austrian Pharmacopoeia, as well as French and Latin sources. Although he initiated the project around 1804, political upheavals delayed its completion by more than three decades.

View Article and Find Full Text PDF

Manual wheelchairs can promote independence among users. However, the user's level of disability, strength, stamina, and the environmental conditions within which the wheelchair is used may limit manual wheelchair functionality. The use of power assist add-ons may mitigate these limitations and help individuals to age in place.

View Article and Find Full Text PDF

The article by Walker et al. (2025) titled "The American Psychological Association and Antisemitism: Toward Equity, Diversity, and Inclusion" regrettably suffers from serious shortcomings in regard to scholarship. These include flawed analyses, an overreliance on unreliable and biased sources, and the presentation of provocative and significant claims without any documentation at all.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!