A case of rituximab-induced hepatitis.

Cancer Biother Radiopharm

Carl and Dorothy Bennett Cancer Center, Stamford, Connecticut 06902, USA.

Published: December 2010

A case of hepatitis in a patient receiving rituximab for ITP is reported. After an extensive workup, no infectious or autoimmune etiology could be found. The authors believe that this represents a case of drug-induced hepatitis, which has not been reported for this agent in the past.

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http://dx.doi.org/10.1089/cbr.2010.0806DOI Listing

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  • Rituximab, an anti-CD20 monoclonal antibody, is commonly used for B-cell lymphomas and has recently been used for treating frequent relapsing nephrotic syndrome, showing a good safety profile with rare lung-related side effects.
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  • After establishing a link between the medication and symptoms, the patient's lung issues were resolved with steroid therapy, marking it as the first documented instance of rituximab-induced lung cystic lesions in India.
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