The title compound, C(19)H(13)Cl(2)NO(3)S, is an N-aryl-sulfonyl derivative of 2-amino-5-chloro-benzophenone. The compound is biologically active and shows potential to be utilized as an inhibitor of CCR2 and CCR9 receptor functions. In the crystal structure, there is an intra-molecular N-H⋯O hydrogen bond between the amide and carbonyl groups. The benzoyl and 4-chloro-phenyl groups form intra-molecular and inter-molecular face-to-face contacts, with a dihedral angle of 10.6 (1)° between their mean planes in both cases, and centroid-centroid separations of 4.00 (1) and 4.25 (1) Å for the intra- and inter-molecular inter-actions, respectively.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2961035 | PMC |
http://dx.doi.org/10.1107/S1600536808007435 | DOI Listing |
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