The title compound, C(18)H(15)ClN(2)O(2), is a potential human immunodeficiency virus type-1 (HIV-1) non-nucleoside reverse transcriptase inhibitor. The pyrrolidine ring adopts an envelope and the diazepine ring a boat conformation. In the crystal structure, two isomers (R and S) form centrosymmetric dimers via N-H⋯O hydrogen bonds.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2960833 | PMC |
http://dx.doi.org/10.1107/S160053680800408X | DOI Listing |
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