The title compound, C(17)H(23)NO(2), contains two chiral centres and was synthesized from 2-(3-acetyl-2,2-dimethyl-cyclo-butyl)acetic acid and m-toluidine. The cyclobutane ring is not flat but flexed as though folded from the dimethyl-substituted C atom to the unsubstituted C atom, with a dihedral angle of 25.9°. The crystal structure is stabilized by N-H⋯O and C-H⋯O hydrogen-bonding inter-actions.
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http://dx.doi.org/10.1107/S160053680706641X | DOI Listing |
Neurosurg Rev
January 2025
Department of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Traumatic Brain Injury (TBI) is a major cause of death, disability, and healthcare expenses worldwide. Decompressive craniectomy (DC) is a critical surgery used when there is uncontrollable swelling in the brain following a TBI. Research has shown that 27.
View Article and Find Full Text PDFPediatr Radiol
January 2025
School of Medicine and Population Health, University of Sheffield, Sheffield, UK.
Background: The European Society of Paediatric Radiology (ESPR) awards prizes for outstanding work presented at their annual scientific meetings. The proportion of ESPR prize-winning abstracts to journal publications is not known. Contextualising abstract-to-publication proportions by evaluating publication experience can yield valuable insights and actionable outcomes to support researchers in overcoming barriers to journal publication.
View Article and Find Full Text PDFJ Taibah Univ Med Sci
February 2025
Department of Prosthodontics/Dental Material, Dr. Ziauddin Ahmad Dental College, Aligarh Muslim University, India.
Objectives: Calcium ions (Ca) play crucial role in tooth development, particularly in maintaining enamel density during amelogenesis. Ameloblasts require specific proteins such as amelogenin, ameloblastin, enamelin, kallikrein, and collagen for enamel growth. Recent research has highlighted the importance of calcium and fluoride ions, as well as the TRPM7, STIM, and SOCE pathways, in regulating various stages of enamel formation.
View Article and Find Full Text PDFAm J Cardiovasc Dis
December 2024
Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences Tehran, Iran.
Background And Aim: Sodium-glucose cotransporter two inhibitors can reduce cardiovascular events by modulating lipid profiles in patients with heart failure, irrespective of diabetes status. In this study, we aimed to assess the effects of SGLT-2 inhibitors on the lipid profiles of patients with heart failure via a meta-analysis.
Methods: The PubMed, Scopus, Web of Science, and Google Scholar databases were searched up to 2023 to retrieve relevant article titles, abstracts, and full texts.
Front Public Health
January 2025
The Third People's Hospital of Ganzhou, Ganzhou, China.
Background: The "Double Reduction" policy requires schools to reduce Chinese students' extracurricular activities and homework to lessen academic stress and improve mental well-being. However, there is limited research on primary school teachers' psychological well-being within the context of the "Double Reduction" policy. This study examined self-reported burnout levels of primary school teachers and investigated the relationship between burnout and depressive symptoms in the context of the "Double Reduction" policy in China.
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