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Blood-based epigenome-wide association study and prediction of alcohol consumption.
Clin Epigenetics
January 2025
Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Alcohol consumption is an important risk factor for multiple diseases. It is typically assessed via self-report, which is open to measurement error through recall bias. Instead, molecular data such as blood-based DNA methylation (DNAm) could be used to derive a more objective measure of alcohol consumption by incorporating information from cytosine-phosphate-guanine (CpG) sites known to be linked to the trait.
View Article and Find Full Text PDFHP1 Promotes the Centromeric Localization of ATRX and Protects Cohesion by Interfering Wapl Activity in Mitosis.
Front Biosci (Landmark Ed)
January 2025
The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province, Hunan Normal University Health Science Center, 410013 Changsha, Hunan, China.
Background: α thalassemia/mental retardation syndrome X-linked (ATRX) serves as a part of the sucrose nonfermenting 2 (SNF2) chromatin-remodeling complex. In interphase, ATRX localizes to pericentromeric heterochromatin, contributing to DNA double-strand break repair, DNA replication, and telomere maintenance. During mitosis, most ATRX proteins are removed from chromosomal arms, leaving a pool near the centromere region in mammalian cells, which is critical for accurate chromosome congression and sister chromatid cohesion protection.
View Article and Find Full Text PDFVitellogenins Level as a Biomarker of the Honeybee Colony Strength in Urban and Rural Conditions.
Insects
December 2024
University of Silesia in Katowice, Faculty of Natural Sciences, Institute of Biology, Biotechnology and Environmen-tal Protection, Research Team of Animal Physiology and Ecotoxicology, Bankowa 9, 40-007 Katowice, Poland.
The study aimed to verify whether urban beekeeping affects the strength of the honeybee () colonies from urban apiaries and the variability of the crucial for their health and long-life protein-vitellogenins. For this purpose, honeybees were kept in two locations-in a city apiary on a roof in the city center and in agricultural areas. Each of the apiaries consisted of six colonies, with the sister queens artificially inseminated with semen from the same pool of drones.
View Article and Find Full Text PDFPhylogenetic and Comparative Genomics Study of Based on Mitochondrial Genomes.
Insects
December 2024
Xinjiang Laboratory of Special Environmental Microbiology, Institute of Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, China.
Camel bot fly () larvae cause myiasis in domesticated and wild camels, resulting in significant economic losses to the camel industry and posing a serious global public health concern. To date, only one mitochondrial genome (mitogenome) of isolated from the Alxa Bactrian camel has been reported. Herein, was isolated from the Junggar Bactrian camel to assemble a complete circular mitogenome with a length of 16,552 bp encoding 13 protein-coding genes, 22 tRNA genes, and two rRNA genes.
View Article and Find Full Text PDFMorphological and Molecular Identification of in Captive Cheetahs () in China Helps Clarify Phylogenetic Relationships with and .
Animals (Basel)
January 2025
Yunnan Key Laboratory for Plateau Mountain Ecology, Restoration of Degraded Environments, School of Ecology and Environmental Sciences, Yunnan University, Kunming 650091, China.
To date, only one case is known where protozoan parasites of the genus were found to infect cheetahs (); the cysts in the musculature were morphologically identified as . Here, we characterized sarcocysts by morphological and molecular methods that were observed in cheetahs who died in zoos in China. Only one type of sarcocyst was present in two of six cheetahs.
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