First identification and characterization of an AdeABC-like efflux pump in Acinetobacter genomospecies 13TU.

Antimicrob Agents Chemother

Department of Microbiology, Hospital Clínic, School of Medicine, University of Barcelona, CRESIB, Barcelona, Spain.

Published: March 2011

Non-Acinetobacter baumannii spp. are emerging among clinical Acinetobacter isolates causing nosocomial infections, and some (such as genomospecies 13TU) appear to be multidrug resistant. The prevalence of non-Acinetobacter baumannii spp. in the hospital setting is likely understated due to poor identification techniques. We report the first identification of an AdeABC-type efflux pump in an Acinetobacter genomospecies 13TU clinical isolate, its contribution to multidrug resistance, and the coexistence of three Ade-type efflux pumps in this strain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3067064PMC
http://dx.doi.org/10.1128/AAC.01142-10DOI Listing

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