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Background: Nurses in long-term care (LTC) and home and community care (HCC) are well acquainted with the high workloads and manifold job stressors that pervade these sectors, making it increasingly difficult to employ and retain a strong workforce. In response, nursing bridging education programs have been proposed to enhance recruitment and retention. While the efficacy of such programs is supported, the transition to practice experience of new nurse graduates is often associated with feelings of under-preparedness.

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Implications of Large Language Models for Clinical Practice: Ethical Analysis Through the Principlism Framework.

J Eval Clin Pract

February 2025

Academic Unit of Population and Lifespan Sciences, School of Medicine, Clinical Sciences Building, University of Nottingham, Nottingham, Nottinghamshire, UK.

Article Synopsis
  • The paper discusses the potential benefits and ethical implications of large language models (LLMs) in healthcare, focusing on how they could enhance patient care and clinical outcomes.
  • LLMs could improve the efficiency of administrative tasks and directly inform clinical decisions but also pose risks of patient harm, necessitating careful risk management.
  • Ethical considerations, particularly around beneficence, autonomy, and justice, suggest that while LLMs can standardize care and reduce biases, patient consent and alternative options must be prioritized to ensure ethical deployment in medical practice.
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The Decision for Amputation Versus Limb Salvage in Patients with Limb-threatening Lower Extremity Indications: An Ethical Analysis.

Orthop Clin North Am

January 2025

Department of Orthopaedic Surgery, Hospital of the University of Pennsylvania, 230 West Washington Square, 5th Floor Farm Journal Building, Philadelphia, PA 19106, USA. Electronic address:

Ethical decision-making in the amputation versus limb salvage context requires consideration of respect for patient autonomy, beneficence, and nonmaleficence. The surgical options demonstrate near equivalent outcomes for traumatic indications, while reconstruction is generally favored for threatened limbs due to diabetic complications. The decision for amputation versus limb salvage must be considered in each individual patient's situation, with a shared decision-making process of paramount importance.

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Shared decision-making (SDM) requires a clear-eyed view of evidence certainty, context, and equipoise in clinical care. This paradigm of care builds on the foundational ethical principle of patient autonomy, further leveraging beneficence, nonmaleficence, and justice to provide bespoke care in the appropriate clinical setting. When evidence is carefully evaluated together with acceptability and feasibility, equity, cost-effectiveness, resources, and patient preferences, an individualized assessment of the trade-off between possible benefits and harms can optimize patient management.

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The healthcare sector significantly contributes to global greenhouse gas (GHG) emissions, with orthopedic surgery generating substantial waste, including single-use devices and hazardous materials. These practices exacerbate climate change and environmental degradation. This article explores the environmental and ethical implications of waste management in orthopedic surgery, focusing on the need for sustainable practices.

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