AI Article Synopsis
- Rheumatoid arthritis (RA) is an inflammatory disease affecting about 1% of the population, with increasing prevalence of lung-related complications.
- RA can impact various parts of the lungs, leading to serious pulmonary issues that account for 10-20% of mortality among patients.
- The occurrence of lung disease in RA patients can differ based on the population studied, the definitions used for lung diseases, and the methods of clinical investigation.
Article Abstract
Rheumatoid arthritis (RA) is a common inflammatory disease, affecting about 1% of the population. Although a major portion of the disease burden including excess mortality is due to its extra-articular manifestations, the prevalence of RA-associated lung disease is increasing. RA can affect the lung parenchyma, airways, and the pleura; and pulmonary complications are directly responsible for 10 to 20% of all mortality. Even though pulmonary infection and drug toxicity are frequent complications of RA, lung disease directly associated with the underlying RA is more common. The prevalence of a particular complication varies based on the characteristics of the population studied, the definition of lung disease used, and the sensitivity of the clinical investigations employed. An overview of lung disease associated with RA is presented here with an emphasis on parenchymal lung disease, pleural effusion, and airway involvement.
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| http://dx.doi.org/10.1016/j.lpm.2010.11.003 | DOI Listing |
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