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Investigation of the participation of the TRPV1 receptor in the irritant effect of dithranol in mice.
Eur J Pharmacol
January 2025
Graduate Program in Pharmacology, Federal University of Santa Catarina (UFSC), 88037-000 - Florianópolis (SC), Brazil. Electronic address:
Dithranol is one of the most effective topical medications for treating plaque psoriasis. However, its clinical use is limited by irritative adverse reactions to the skin, such as oedema, erythema, and pruritus, caused by poorly understood mechanisms. Because TRPV1 activation mediates skin irritation caused by several drugs, we conducted blind and randomised experiments in male and female C57BL/6 mice to elucidate the role of TRPV1 in dithranol-induced irritation.
View Article and Find Full Text PDFTermination of Resuscitation Rules for In-Hospital Cardiac Arrest.
JAMA Intern Med
January 2025
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Importance: There are no validated decision rules for terminating resuscitation during in-hospital cardiac arrest. Decision rules may guide termination and prevent inappropriate early termination of resuscitation.
Objective: To develop and validate termination of resuscitation rules for in-hospital cardiac arrest.
Correlation of Burnout Syndrome with Emotional Intelligence among Clinicians at Workplace.
Pak J Med Sci
January 2025
Muhammad Babar Khan, Khyber Medical College, Peshawar, Pakistan.
Objective: To determine the correlation of burnout syndrome with emotional intelligence at workplace.
Methods: This cross-sectional study was conducted in six public sector hospitals of Khyber Pakhtunkhwa between June and November, 2022. Male and female clinicians from Medicine, Surgery, Obstetrics / Gynaecology, Paediatrics Medicine, Paediatric Surgery, Gastroenterology, Anesthesiology, Psychiatry, Radiology, Dermatology, Ophthalmology, Otorhinolaryngology, Nephrology, Urology, Neurology, Neurosurgery, Orthopaedics, Endocrinology, Rheumatology and Cardiology were included in the study.
Advances and stagnation in airway surgery: A historical perspective.
Cir Esp (Engl Ed)
January 2025
Thoracic Surgery Department, Hospital Universitari de la Ribera, Alzira, València, Spain.
Airway pathology is a complex and incompletely mastered field. Historically, its management was rudimentary, with tracheostomies performed in ancient Egypt, and progress remained stagnant for millennia. Significant advances began in the late 19 century, followed by notable surgical and anesthetic progress in the mid-20 century.
View Article and Find Full Text PDFEmerging trends in pharmacological treatment of inferior alveolar nerve sensory disorders: a scoping review.
Med Oral Patol Oral Cir Bucal
January 2025
Department of Oral and Maxillofacial Surgery and Traumatology University of Pernambuco. Av. Gov. Agamenon Magalhães Santo Amaro, Recife - PE, CEP 50100-010, Brazil
Background: Sensory disorders of the inferior alveolar nerve, often arising from dental procedures, markedly impact the quality of life of patients. This article proposes a scoping review to analyze emerging trends in pharmacological treatment for these disorders, addressing scientific gaps and clinical practices.
Material And Methods: The review followed the PRISMA-ScR protocol, conducting data searches across various databases, including PubMed and Cochrane, until March 2024.
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