Introduction: we reviewed transfusion practice following primary hip and knee arthroplasty with emphasis on the relationship between surgeon volume and the need for transfusion.
Materials/methods: review of a consecutive series of 508 primary, elective, unilateral arthroplasties (248 THR/260 TKR) performed over a 12-month period. Data were analysed to determine the overall rate of transfusion and the details of any such transfusion. Secondarily, multivariate regression was performed to determine the effects of surgeon volume and other recorded variables upon the need for transfusion. For the purpose of analysis we classified surgeons doing more than 52 arthroplasties a year as "high volume" and surgeons performing less than this number as "low volume".
Results: transfusion rates were 10% and 7% following THR and TKR. Multivariate analysis demonstrated that surgeon volume (<52 operations/yr vs. >52 operations/yr) and preoperative Hb<12g/dl were the only significant determinants of a need for postoperative transfusion (p<0.01). High volume and low volume surgeons transfused 5% vs. 17%, respectively (RR=3.3 (95%CI 1.5-9.1) p=0.003) following THR and 4% vs. 13% (RR=3.6 (95%CI 1.4-9.3) p=0.006) following TKR.
Discussion And Conclusion: High volume surgeons have significantly lower transfusion rates when compared to nationally accepted figures.
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http://dx.doi.org/10.1016/j.surge.2010.08.011 | DOI Listing |
J Nephrol
January 2025
Department of Nephrology, Beaumont Hospital, Dublin, Ireland.
Background: Autosomal dominant polycystic kidney disease (ADPKD) is caused primarily by pathogenic variants in the PKD1 and PKD2 genes. Although the type of ADPKD variant can influence disease severity, rare, hypomorphic PKD1 variants have also been reported to modify disease severity or cause biallelic ADPKD. This study examines whether rare, additional, potentially protein-altering, non-pathogenic PKD1 variants contribute to ADPKD phenotypic outcomes.
View Article and Find Full Text PDFDis Colon Rectum
January 2025
Center for Pelvic Floor Disorders, Department of Surgery, Colorectal Surgery Section, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Background: Ventral rectopexy has become increasingly utilized in the surgical management of rectal prolapse. There is a need for a contemporary evaluation of the role of the procedure and description of its use in clinical practice.
Objective: To create an international consensus on ventral rectopexy.
J Orthop Traumatol
January 2025
Italian National Registry of Implantable Prostheses (RIPI), Italian National Institute of Health, Viale Regina Elena 299, 00161, Rome, Italy.
Background: Treatment of ankle osteoarthritis by total ankle replacement (TAR) is increasing worldwide. The aim of the study was to present the overall temporal trends of TAR throughout 22 years (2001-2022) in Italy, analyzing the distributions of hospitals by volume of activity and patients by age and sex, drawing on the National Hospital Discharge Record database. Furthermore, as a secondary aim, we compared these trends with those of ankle fusions.
View Article and Find Full Text PDFJ Nephrol
January 2025
Department of Nephrology and Transplantation, Beaumont Hospital, Dublin, Ireland.
Background: Autosomal Dominant Polycystic Kidney Disease (ADPKD) represents the most common monogenic cause of kidney failure. While identifying genetic variants predicts disease progression, characterization of recently described ADPKD-like variants is limited. We explored disease progression and genetic spectrum of genetically-confirmed ADPKD families with PKD1 and non-PKD1 variants.
View Article and Find Full Text PDFInt Ophthalmol
January 2025
Ophthalmology Department, Faculty of Medicine - Suez Canal University Hospitals, 4.5 Kilo - Ring Road, Ismailia, 41522, Egypt.
Purpose: To assess the effect of anterior chamber depth on corneal endothelium using specular microscopy following uneventful phacoemulsification among cataract patients with different axial lengths.
Methods: The study was conducted in a quasi-experimental design including 300 eyes of 300 patients with grade three age-related nuclear cataract distributed equally based on their axial length into three equal groups. All eyes had grade three nuclear cataract.
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