AI Article Synopsis
- A new C-glucosylflavone and a megastigmane glycoside were discovered from methanol extracts of Ficus microcarpa leaves, along with twelve other known compounds.
- Their chemical structures were identified using advanced techniques like mass and NMR spectroscopy.
- The antioxidant activities of these compounds were significant, with several showing a strong capacity to reduce copper (I) ions and effective antioxidant properties compared to Trolox standards.
Article Abstract
By bioactive-guided fractionation of methanol extract of the Ficus microcarpa leaves, one new C-glucosylflavone, ficuflavoside (1), one new megastigmane glycoside, ficumegasoside (8), and twelve known compounds including flavonoids (2-6), phenylpropanoids (7), megastigmanes (9-11) and sterol derivatives (12-14) were isolated. Their chemical structures were elucidated by mass, 1D, and 2D NMR spectroscopies. The antioxidant activities of these compounds were measured using the oxygen radical absorbance capacity methods. Compounds 1-6 exhibited potent antioxidant activities of 6.6-9.5μM Trolox equivalents at the concentration of 2.0μM. The results indicated 2, 3, and 5 having meaningful reducing capacity of copper (I) ions concentration of 6.1-8.4μM.
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| http://dx.doi.org/10.1016/j.bmcl.2010.12.025 | DOI Listing |
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