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http://dx.doi.org/10.4161/cc.10.1.14288 | DOI Listing |
Aquat Toxicol
November 2024
Shandong Key Laboratory of Marine Ecological Restoration, Shandong Marine Resources and Environment Research Institute, Yantai, 264006, PR China. Electronic address:
Nano-zinc oxide (ZnO NPs), as widely used nanomaterials, are inevitably released into aquatic environments, posing potential threats to aquatic organisms. Mytilus galloprovincialis is a bivalve species sensitive to changes in marine ecological environments, but there has been limited research on its toxicity response to ZnO NPs. Therefore, we selected M.
View Article and Find Full Text PDFCells
June 2024
Department of Cell Biology, Federal University of Paraná, Curitiba 81531-980, PR, Brazil.
In the original publication [...
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2024
Eco-environmental Protection Research Institute, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China; Agricultural Environment and Farmland Conservation Experiment Station of Ministry Agriculture, Shanghai 201403, China. Electronic address:
Eisenia fetida is recognised as advantageous model species in ecotoxicological and regeneration investigations. The intensive utilization of carbamate pesticides (CARs) imposes heavy residue burdens and grave hazards on edaphic environments as well as soil fauna therein. However, precise mechanisms whereby the specific CAR exerted toxic effects on earthworms remain largely elusive, notably from regenerative perspective.
View Article and Find Full Text PDFCancer Drug Resist
July 2023
Department of Experimental and Clinical Medicine, "Magna Graecia" University of Catanzaro, Catanzaro 88100, Italy.
Early identification of breast cancer (BC) patients at a high risk of progression may aid in therapeutic and prognostic aims. This is especially true for metastatic disease, which is responsible for most cancer-related deaths. Growing evidence indicates that the translationally controlled tumor protein (TCTP) may be a clinically relevant marker for identifying poorly differentiated aggressive BC tumors.
View Article and Find Full Text PDFCancer Genomics Proteomics
November 2022
Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Mainz, Germany;
Background/aim: Artemisinin and its derivatives are not only approved antimalarial drugs but also exert strong anticancer activity. Based on the clinical activity of artesunate (ART) that has been previously reported in cervix carcinoma, we investigated a panel of 12 different biomarkers and identified the Wilms Tumor 1 (WT1) protein as a potential target of ART.
Patients And Methods: Matched biopsies of cervical carcinoma before, during, and after therapy from patients treated with ART were investigated for induction of apoptosis (TUNEL assay) and expression of Wilms Tumor protein 1 (WT1), 14-3-3 ζ, cluster of differentiation markers (CD4, CD8, CD56), ATP-binding cassette transporter B5 (ABCB5), glutathione S-transferase P1 (GSTP1), inducible nitric oxide synthase (iNOS), translationally controlled tumor protein (TCTP), eukaryotic elongation factor 3 (eIF3), and ADP/ATP translocase by immunohistochemistry.
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