Endotoxins and β-glucans are one of the major markers of microbiological contamination. As components of biological aerosols, they are ubiquitous in many environments. Numerous studies performed during the last three decades have proved that exposure to endotoxins and β-glucans could be associated with many diseases and/or adverse health outcomes. The aim of this review is to present the current stage of knowledge regarding endotoxins and β-glucans as biologically active components of aerosols and to characterize the quantitative methods for their detection in environmental samples. The problems of occupational exposure to both these components and their control procedures are also discussed. An overview of the available worldwide and Polish standards and threshold limit values is also given.
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Int J Nanomedicine
January 2025
Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, People's Republic of China.
Introduction: Acute respiratory distress syndrome (ARDS) is a life-threatening type of acute lung injury (ALI) characterized by elevated mortality rates and long-term effects. To date, no pharmacological treatment has proven effective for ARDS. Mesenchymal stem cell-derived apoptotic vesicles (apoVs) were recently found to have excellent therapeutic potential for inflammatory diseases.
View Article and Find Full Text PDFToxicol Res
January 2025
Department of Biochemistry, College of Natural Sciences, Kangwon National University, 24341 Chuncheon, Republic of Korea.
Unlabelled: Lipopolysaccharide (LPS), a gut-derived endotoxin, is a recognized risk factor for both Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). Rocaglamide-A (Roc-A), a natural compound derived from the genus Aglaia, is known for its pharmacological and immunosuppressive effects on various cell types. Although our recent investigations have unveiled Roc-A's anti-adipogenic role in adipocytes, its mechanism in hepatic inflammation remains elusive.
View Article and Find Full Text PDFJ Periodontal Res
January 2025
Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK.
Aim: To evaluate the diagnostic accuracy of microbiome-derived biomarkers for periodontitis in oral fluids (saliva and subgingival samples).
Methods: This systematic review followed PRISMA guidelines. Electronic searches were performed across multiple databases from December 2022 to November 2024.
Small
January 2025
BASF SE, Dept. Analytical & Material Science, 67056, Ludwigshafen, Germany.
Assessing the inhalation hazard of microplastics is important but necessitates sufficient quantity of microplastics that are representative and respirable (<4 µm). Common plastics are not typically manufactured in such small sizes. Here, solvent precipitation is used to produce respirable test materials from thermoplastics polyurethane (TPU), polyamide (PA-6), polyethylene terephthalate (PET), and low-density polyethylene (LDPE).
View Article and Find Full Text PDFJ Oral Facial Pain Headache
June 2024
Department of Geriatrics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 310003 Hangzhou, Zhejiang, China.
Trigeminal neuralgia (TN) is a debilitating condition affecting the patients' life quality. New therapeutic approaches and novel drugs are required to treat TN. Trazodone being a serotonin antagonist and reuptake inhibitor (SARI) provides neuroprotection, however its role and underlying mechanism in TN or are not clear.
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