Morecambe's three EU designated bathing beaches frequently fail the EU directives, even after a state of the art sewage treatment plant has become operational. We have been using conventional microbiology to look at the seasonality and distribution of indicator and pathogenic bacteria in Morcambe Bay and using molecular methods (polymerase chain reaction (PCR) and pulse field gel electrophoresis (PFGE)) to investigate the pathways by which pathogens reach the bathing waters. We will present data for Morecambe Bay which show that: 1. Failures and passes appear to be associated with the prevailing climatic conditions. 2. Indicator bacteria may not always be derived from sewage effluents. 3. Not all pathogens are distributed in the same way as indicator bacteria. 4. Pathogens such as Campylobacter are as likely to come from birds as from sewage.
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http://dx.doi.org/10.1111/j.1365-2672.1998.tb05288.x | DOI Listing |
BMC Med
January 2025
Department of Oncology, University of Oxford, Oxford, UK.
Background: The clinical translation of positron emission tomography (PET) radiotracers for cancer management presents complex challenges. We have developed consensus-based recommendations for preclinical and clinical assessment of novel and established radiotracers, applied to image different cancer types, to improve the standardisation of translational methodologies and accelerate clinical implementation.
Methods: A consensus process was developed using the RAND/UCLA Appropriateness Method (RAM) to gather insights from a multidisciplinary panel of 38 key stakeholders on the appropriateness of preclinical and clinical methodologies and stakeholder engagement for PET radiotracer translation.
Pragmat Obs Res
January 2025
Lancaster Medical School, Lancaster University, Lancaster, UK.
J Comput Assist Tomogr
November 2024
Department of Trauma and Orthopaedics, University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom.
Computed tomography plays an ever-increasing role in the management of fractures and dislocations due to its capability in efficiently providing multiplanar reformats and 3-dimensional volume rendered images. It can reveal findings that are occult on plain radiography and therefore allow for more accurate decision making with regard to fracture classification and management. Clinical radiologists play a critical role in facilitating the processing of imaging to provide adequate image reformats in the desired planes, producing 3 dimensional images but most crucially identifying pertinent findings, which will contribute between the selection of nonoperative and operative management and potentially influence surgical technique.
View Article and Find Full Text PDFRheumatology (Oxford)
December 2024
Department of Rheumatology, University Hospitals of Morecambe Bay NHS Foundation Trust, Royal Lancaster Infirmary, Lancaster, UK.
Br J Community Nurs
December 2024
Specialist Nurse in Tissue Viability, University Hospitals of Morecambe Bay, NHS Foundation Trust.
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