Aim: To build a easy and reliable rat model of insulin resistance.
Methods: Changes concerning sugar metabolism were observed in experimental rats injected intraperitoneally by different doses of dexamethasone.
Results: The changes by dexamethasone in fasting blood insulin and insulin resistance prior to that of fasting blood glucose were dose and time dependent.
Conclusion: It was convenience to set up a insulin resistance model induced by dexamethasone in rats which would favor other related research.
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