Keratoconus association with axial myopia: a prospective biometric study.

Eye Contact Lens

Department of Ophthalmology, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.

Published: January 2011

Objectives: To determine if the axial length and its components are significantly different between a keratoconic eye and an emmetropic eye and also to determine if the degree of corneal ectasia is associated with axial myopia in a keratoconic eye.

Methods: A prospective observational study was conducted with keratoconic patients and emmetropic controls. All subjects underwent corneal topography analysis and axial length measurement by immersion-ultrasound biometry. Statistical methods were employed to compare the two groups and to ascertain whether any associations exist.

Results: The axial length, anterior chamber depth, and posterior segment length were all significantly longer in the keratoconic group (n=41) than in the emmetropic control group (n=33) in a statistically significant fashion. The mean keratoconic axial length was 24.40 vs. 23.24 mm for the emmetropic group (P=0.001). The mean keratometry for the keratoconic group correlated with spherical equivalence and visual acuity in statistically significant manners but not with axial length.

Conclusions: Keratoconic eyes have on average longer axial lengths that are primarily because of longer posterior segment lengths than emmetropic eyes. This finding should be considered in keratoconic patients undergoing keratoplasty because it relates to postkeratoplasty refractive outcomes.

Download full-text PDF

Source
http://dx.doi.org/10.1097/ICL.0b013e3181fb2119DOI Listing

Publication Analysis

Top Keywords

axial length
16
axial
8
axial myopia
8
keratoconic
8
keratoconic patients
8
posterior segment
8
keratoconic group
8
length
5
emmetropic
5
keratoconus association
4

Similar Publications

Surgical Parameters and Prognostic Factors in Persistent Fetal Vasculature: Insights from a Retrospective Cohort Study.

Ophthalmol Ther

January 2025

Pediatric Ophthalmology and Strabismus Division, King Khaled Eye Specialist Hospital, Al Urubah Branche Rd., West Building 2nd Floor, 11462, Riyadh, Saudi Arabia.

Introduction: Persistent fetal vasculature (PFV) is a congenital anomaly associated with significant surgical challenges, including a high risk of postoperative retinal detachment (RD). This study aimed to evaluate the impact of surgical approach and axial length (AL) on RD risk and visual outcomes in pediatric PFV management.

Methods: A retrospective cohort study was conducted involving 76 eyes of 74 patients who underwent cataract surgery for PFV between 2014 and 2022.

View Article and Find Full Text PDF

Refractive error maps: A predictive tool for refractive error progression.

Ophthalmic Physiol Opt

January 2025

Faculty of Health, Medicine and Social Care, Medical Technology Research Centre, Anglia Ruskin University, Chelmsford, UK.

Purpose: To investigate the influence of axial length on different ocular parameters and create a predictive tool for refractive error progression.

Methods: Two eye models were used to simulate refractive errors, namely the Liou-Brennan and the Goncharov-Dainty. Both models were simulated using Zemax OpticStudio.

View Article and Find Full Text PDF

Purpose: To assess the relationship between angle kappa (apparent chord mu) and ocular parameters in cataract patients.

Methods: In this cross-sectional study, the data on apparent chord mu, age, axial length, anterior chamber depth, anterior and posterior mean keratometry, mean total keratometry, white-to-white, central corneal thickness and lens thickness were collected for consecutive cataract patients. Correlation (Pearson) between chord mu and the other ocular parameters was calculated.

View Article and Find Full Text PDF

Eye Axial Length: Is There a Protective Link to Diabetic Retinopathy?

Cureus

December 2024

Optics and Optometry Division, Investigative Techniques in Optometry Research Group, Department of Biomedical Sciences, University of West Attica, Athens, GRC.

Diabetic retinopathy (DR) is a leading cause of vision impairment and blindness globally, particularly among working-age adults. As the prevalence of diabetes continues to rise, understanding factors that influence DR development and progression is increasingly important. Recent studies suggest a protective association between a longer axial length (AL) of the eye and the risk of DR, particularly in myopic individuals.

View Article and Find Full Text PDF

Cerebrospinal fluid dynamics and subarachnoid space occlusion following traumatic spinal cord injury in the pig: an investigation using magnetic resonance imaging.

Fluids Barriers CNS

January 2025

Adelaide Spinal Research Group & Centre for Orthopaedics and Trauma Research, Faculty of Health and Medical Sciences, The University of Adelaide, Level 7, Adelaide Health and Medical Sciences Building, North Terrace, Adelaide, SA, 5005, Australia.

Background: Traumatic spinal cord injury (SCI) causes spinal cord swelling and occlusion of the subarachnoid space (SAS). SAS occlusion can change pulsatile cerebrospinal fluid (CSF) dynamics, which could have acute clinical management implications. This study aimed to characterise SAS occlusion and investigate CSF dynamics over 14 days post-SCI in the pig.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!