Bacteriological examination of sputum smears of 42 patients with anthracotic tuberculosis divided according to the activity of a tuberculous process into 2 groups was undertaken. To achieve the growth of L-forms, sputum inoculation was done on Shkolnikova's semiliquid culture medium. Phase contrast microscopic examination of the sputum smears was carried out at 280 X magnification. As the pneumoconiotic process in patients with anthracotic pulmonary tuberculosis grows progressively worse, the rate of typical Mycobacterium strain positivity decreases, while the rate and intensity of L-forms excretion proportionally increase. In the patients with inactive forms of anthracotic tuberculosis, the bacillary excretion was characterized by monomorphism of vacuolized L-forms. At the same time, active forms of anthracotic tuberculosis were accompanied by a massive excretion of Myco. L-forms and featured a wide range of morphologic changes dominated by giant cells, cord-factor, heterogeneous granulation and homogeneous mass as a consequence of overall destruction of the cell membranes.
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Cureus
October 2024
Pulmonology and Critical Care, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
A clinical entity that was reported less than ten years ago, bronchial anthracofibrosis is marked by multifocal bronchial lumen constriction and anthracotic coloring of the bronchial mucosa. There is various etiology associated with "black bronchoscopy". A 47-year-old woman with no known co-morbidities reported having a three-month history of coughing up sputum.
View Article and Find Full Text PDFOpen Respir Med J
May 2022
Institute for Transformative Molecular Medicine, Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH 44106, United States.
Background: Exposure to toxic materials predisposes the lungs to infectious agents and inflammatory responses. The present study was performed on patients with anthracosis caused by exposure to fossil fuels in previous years, and histopathological features of airways' normal-appearing tissue were compared with histopathological features of anthracotic plaques in these patients.
Methods: Bronchoscopic evaluations were performed on bakery workers who were directly in contact with fossil fuels.
Rev Mal Respir
March 2021
Service des maladies respiratoires, Professeur Tunon-de-Lara, CHU de Bordeaux, avenue de Magellan, 33604 Pessac, France.
Introduction: Pneumoconiosis is defined as a diffuse interstitial lung disease secondary to inhalation of mineral particles. Haemoptysis is common in pneumoconiosis. But it is usually secondary to bronchiectasis, bronchitis or pulmonary tuberculosis occurring with silicosis.
View Article and Find Full Text PDFCurr Probl Diagn Radiol
October 2021
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Prolonged exposure to biomass fuel smoke is a proven irritant, known to aggravate chronic lung diseases. Of the myriad spectrum of thoracic manifestations associated with inhalation of biomass fuel smoke, bronchial anthracofibrosis is a recently described entity characterized by bronchial narrowing and visible anthracotic pigmentation on bronchoscopy. Common imaging features include bronchostenosis, peribronchial soft tissue with or without calcification along with peribronchial lymph nodes.
View Article and Find Full Text PDFMonaldi Arch Chest Dis
December 2019
Department of Respiratory Medicine, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry.
Ulceration in the bronchial mucosa is noted rarely in bronchoscopy. In the past, it was frequently encountered in endobronchial tuberculosis. Deep necrotic bronchial ulcers are seen very rarely in clinical practice.
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