Perianal complications occur in approximately 33% of patients with Crohn's disease, and may be the most prominent or even the presenting complaint suggestive of a diagnosis of Crohn's disease. A case is reported of severe perianal Crohn's disease with anal destruction and incontinence that developed after perianal surgery. Healing of perianal lesions and recovery of anal function was achieved with infliximab therapy.
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| http://dx.doi.org/10.2165/11586270-000000000-00000 | DOI Listing |
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