AI Article Synopsis
- The reaction between α-oxo-aldoximes and PhI(OAc)(2) results in the formation of α-oxo-nitrile oxides.
- α-oxo-ketoximes undergo oxidative cleavage, transforming into nitrile oxides, which can then be trapped by norbornene or styrene with good yields.
- The reaction is less effective for α,α'-dioxo-ketoximes.
Article Abstract
Upon reaction with PhI(OAc)(2), α-oxo-aldoximes are oxidized to α-oxo-nitrile oxides, while α-oxo-ketoximes are converted into nitrile oxides via the oxidative cleavage of the carbonyl-imino σ bond. The nitrile oxides thus formed were trapped with norbornene or styrene in good yield. α,α'-Dioxo-ketoximes react less efficiently.
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| http://dx.doi.org/10.1021/jo102241s | DOI Listing |
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