The copying of chromosomal DNA initiates from a single nucleoprotein assembly called the prereplication complex. New findings in a recent issue of Molecular Cell (Yardimci et al., 2010) reveal that this complex dissolves into two independent replisomes that move away from each other as DNA synthesis ensues.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023982 | PMC |
http://dx.doi.org/10.1016/j.molcel.2010.12.014 | DOI Listing |
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