DNA replication: making two forks from one prereplication complex.

Mol Cell

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.

Published: December 2010

The copying of chromosomal DNA initiates from a single nucleoprotein assembly called the prereplication complex. New findings in a recent issue of Molecular Cell (Yardimci et al., 2010) reveal that this complex dissolves into two independent replisomes that move away from each other as DNA synthesis ensues.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023982PMC
http://dx.doi.org/10.1016/j.molcel.2010.12.014DOI Listing

Publication Analysis

Top Keywords

prereplication complex
8
dna replication
4
replication making
4
making forks
4
forks prereplication
4
complex copying
4
copying chromosomal
4
chromosomal dna
4
dna initiates
4
initiates single
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!