Both the design considerations and the dosimetric properties of the Siemens Model 5800 linear accelerator are discussed. This unit is of such an energy (3.3 MV) as to imitate Cobalt-60 teletherapy depth doses. A linear relation of dmax to depth dose at low energies was found for various wave guides and targets. The energy of the unit can be characterized by its nominal accelerating potential of 2.70 MV, its d80 of 5.3 cm, its first half-value layer of 0.8 cm lead and the measured energy of the electron beam at 3.3 MeV. The following selected commissioning aspects are reported: central axis depth dose, relative output factors, beam profiles, wedge factors, virtual source position, back scatter factors, penumbra and build-up region.
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Sci Rep
January 2025
Radiation Safety and Quality Assurance division, National Cancer Center Hospital East, Chiba, 277-8577, Japan.
The impact of three-dimensional (3D) dose delivery accuracy of C-arm linacs on the planning target volume (PTV) margin was evaluated for non-coplanar intracranial stereotactic radiosurgery (SRS). A multi-institutional 3D starshot test using beams from seven directions was conducted at 22 clinics using Varian and Elekta linacs with X-ray CT-based polymer gel dosimeters. Variability in dose delivery accuracy was observed, with the distance between the imaging isocenter and each beam exceeding 1 mm at one institution for Varian and nine institutions for Elekta.
View Article and Find Full Text PDFCureus
December 2024
Radiation Oncology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, IND.
Introduction: Brain arteriovenous malformations (AVM) are complex vascular pathologies with a significant risk of hemorrhage. Stereotactic radiosurgery (SRS) is an effective treatment modality for AVM, initially popularized on the Gamma Knife (Elekta AB, Stockholm, Sweden) platform, and now benefits from the modern advances in linear accelerator (LINAC)-based platforms. This study evaluates the outcomes of LINAC-based SRS/hypofractionated stereotactic radiotherapy (hFSRT) for cerebral AVMs.
View Article and Find Full Text PDFACS Nano
January 2025
School of Electrical Engineering, Korea University, Seoul 02841, Republic of Korea.
Organic photodiodes (OPDs) are a significant focus for the next-generation of light-detection technologies. However, organic semiconductors in OPDs still face key challenges, such as low carrier mobilities and limited efficiency in generating photon-induced signals, which affect the detectable resolution and dynamic range. In this study, the characterization of the interaction between organic polymeric bulk heterojunctions and two-dimensional (2D) transition metal dichalcogenides (MoS) reveals an enhancement in photocurrent due to improved photogeneration dynamics (e.
View Article and Find Full Text PDFPhys Med
January 2025
Centre for Medical Radiation Physics, University of Wollongong Australia, Wollongong, NSW 2522, Australia.
Purpose: To propose comprehensive characterization methods of additive manufacturing (AM) materials for MV photon and MeV electron radiotherapy.
Methodology: This study investigated 15 AM materials using CT machines. Geometrical accuracy, tissue-equivalence, uniformity, and fabrication parameters were considered.
BMC Pregnancy Childbirth
January 2025
Centre for Clinical Epidemiology, Lady Davis Research Institute, Montreal, Québec, Canada.
Background: Lower maternal insulin sensitivity during pregnancy is associated with greater fetal adiposity. Physical activity can improve insulin sensitivity, but it is not known if physical behaviours influence the known association of maternal insulin sensitivity with offspring adiposity. This study aimed to investigate the moderating impact of physical behaviours on this association.
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