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http://dx.doi.org/10.1007/s11671-010-9819-3 | DOI Listing |
Langmuir
January 2025
Interdisciplinary Research Center in Biomedical Materials (IRCBM), COMSATS University Islamabad (CUI), Lahore Campus, Lahore 54000, Pakistan.
By integrating iron-cobalt squarate bimetallic metal-organic framework (Fe-Co-SqBMoF) based smart material (SM) with functional DNA (fDNA), we designed a target responsive fDNA@Fe-Co-SqBMoF bioelectrode that exhibits recognition induced switchable response to serve as a reagentless single step electrochemical apta-switch (REA). The construct takes advantage of fDNA ability to bind and concentrate target on the receptor interface, while Fe-Co-SqBMoF@SM multifeatures to serve as an immobilization matrix and a signal generating electrochemical switch. Fe-Co-SqBMoF was introduced to prepare a redox active pencil graphite electrode (PGE), while fDNA (aptamer) was decorated on the receptor PGE to impart specificity and selectivity.
View Article and Find Full Text PDFImeta
December 2024
Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Shenzhen China.
The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.
View Article and Find Full Text PDFBiosci Trends
January 2025
Faculty of Hepato-Pancreato-Biliary Surgery, the First Medical Center of the Chinese PLA General Hospital, Institute of Hepatobiliary Surgery of the Chinese PLA, Beijing, China.
Up to half of hepatocellular carcinoma (HCC) cases are diagnosed at an advanced stage, for which effective treatment options are lacking, resulting in a poor prognosis. Over the past few years, the combination of immune checkpoint inhibitors and anti-angiogenic targeted therapy has proven highly efficacious in treating advanced HCC, significantly extending patients' survival and providing a potential for sequential curative surgery. After sequential curative hepatectomy or liver transplantation following conversion therapy, patients can receive long-term survival benefits.
View Article and Find Full Text PDFAge Ageing
November 2024
Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Background: Immunity and inflammation may be essential to the pathogenesis of dementia. However, the association of immune-mediated diseases with the risk of incident dementia has not been well characterised.
Objectives: We aimed to investigate the prospective association of 27 immune-mediated diseases and incident dementia risk and to explore the underlying mechanisms driven by brain structures.
Cureus
November 2024
Gastroenterological Surgery, Saitama Medical University International Medical Center, Hidaka, JPN.
The Senhance robotic system (Asensus Surgical, Durham, NC, USA) is an innovative platform for minimally invasive surgery. It enables surgeons to perform precise and cost-effective procedures using reusable instruments and has advanced features such as haptic feedback and eye-tracking camera control. Herein, we present the first application of the "double bipolar method" (DBM) in a Senhance-assisted laparoscopic partial cystectomy utilizing 3 mm Maryland bipolar instruments.
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