Background: Chromomycosis is a subcutaneous mycosis caused by dematiaceous fungi. It is characterized by the presence of nodules, verrucous and atrophic lesions, and is prevalent in tropical and subtropical areas. Mexico ranks third among the subcutaneous mycoses, mainly affecting the lower limbs. The verrucous lesions are the most common clinical presentation.
Aims: We present a case of chromomycosis located in the helix and the left earlobe in a 29 year-old male, with unusual morphology and topography.
Method: Samples from the affected ear were taken for direct examination, and cultured in Sabouraud dextrose agar and mycobiotic agar.
Results: Fumagoid cells were found when examining the lesion scrapings under direct microscopic examination. The Sabouraud dextrose agar and mycobiotic agar developed a colony of black fungus, which in the microscopic study was identified as Fonsecaea pedrosoi. The definitive diagnosis was chromomycosis, a pathology that was treated with itraconazole 200mg daily for 10 weeks, with a complete resolution of the dermatosis.
Conclusions: This is a case of chromomycosis with unusual clinical features, with an appropriate response to treatment with itraconazole.
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http://dx.doi.org/10.1016/j.riam.2010.11.006 | DOI Listing |
Am J Trop Med Hyg
December 2024
Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Chromoblastomycosis (CBM), a prevalent subcutaneous mycosis in tropical and subtropical regions caused by dematiaceous fungi, often presents as refractory lesions. This case report details a 63-year-old woman from Tianjin, China, with CBM caused by Cladophialophora carrionii after plant trauma. Successful treatment with itraconazole was performed.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
December 2024
Department of Dermatology and Venereology, The Third Affiliated Hospital, Southern Medical University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, Guangzhou, PR China. Electronic address:
Background: 5-aminolevulinic acid photodynamic therapy (ALA-PDT) has received growing attention for treating chromoblastomycosis (CBM) and has shown efficacy in a handful of clinical case reports. However, there is insufficient information regarding the effects of ALA-PDT on Fonsecaea monophora in mouse infection model and the related mechanisms. This study investigated these issues in vivo.
View Article and Find Full Text PDFIndian J Dermatol
October 2024
Department of Dermatology, Institute of Child Health, Kolkata, India.
Introduction: Deep mycoses acquired by penetrating trauma to the skin can have varied and sometimes atypical morphological presentations resulting in diagnostic dilemmas and delay in treatment onset. Histopathology can be a useful tool in not only diagnosing but also differentiating various deep mycoses.
Aims And Objectives: To observe various morphological presentations and histopathological features of deep fungal infections.
Cureus
November 2024
Dermatology, University of California Davis Medical Center, Sacramento, USA.
Chromoblastomycosis is an uncommon, chronic granulomatous fungal infection of the skin and subcutaneous tissue. Chromoblastomycosis is most commonly caused by the traumatic inoculation of dematiaceous (pigmented) fungi, most commonly species, species, and species. Chromoblastomycosis usually affects agricultural workers in tropical and subtropical climates.
View Article and Find Full Text PDFCureus
October 2024
Family Medicine, St. Joseph's Regional Medical Center, Paterson, USA.
This is the case of chronic chromoblastomycosis (CBM) in a 61-year-old male from the Dominican Republic (DR) with extensive cutaneous eruptions over multiple areas of the body including bilateral lower extremities and the flank extending to the back. A 61-year-old male with a history of morbid obesity, chronic kidney disease stage III, and well-controlled hypertension presented to the family medicine clinic for the evaluation of chronic painful skin lesions on his legs and torso. The lesions began 19 years prior, following a flood in the Dominican Republic (DR) where he was living at the time.
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