Pharmacological correction of testosterone deficiency during experimental myocardial ischemia.

Bull Exp Biol Med

Department of Neuropharmacology, Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia.

Published: October 2010

Experiments on rats with myocardial ischemia modeled by occlusion of the left coronary artery aggravated by alimentary dislipoproteinemia showed that therapy with taurepar (50 mg/kg), a taurine derivative, decreased blood corticosterone concentration and increased the level of endogenous testosterone, which attests to normalization of the compensatory-adaptive and gonadotropic functions of the organism.

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http://dx.doi.org/10.1007/s10517-010-1003-3DOI Listing

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