The perturbation method is combined with the Rigorous CoupledWave Analysis (RCWA) to enhance its computational speed. In the original RCWA, a grating is approximated by a stack of lamellar gratings and the number of eigenvalue systems to be solved is equal to the number of subgratings. The perturbation method allows to derive the eigensolutions in many layers from the computed eigensolutions of a reference layer provided that the optical and geometrical parameters of these layers differ only slightly. A trapezoidal grating is considered to evaluate the performance of the method.
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http://dx.doi.org/10.1364/OE.18.026274 | DOI Listing |
Quant Imaging Med Surg
January 2025
Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Volumetric modulated arc therapy (VMAT) is a popular radiotherapy technique in the clinic. As consisting of hundreds of control points in a VMAT plan it is more complex and time consuming than those conventional treatment modalities, such as intensity modulated radiation therapy. To improve the efficiency and accuracy of its quality assurance procedure, a novel automated anomaly detection method was proposed.
View Article and Find Full Text PDFJ Transl Med
January 2025
Department of Endocrine Medicine, Shanghai Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201306, Chin, China.
Background And Objective: Mitochondria are crucial to the function of renal tubular cells, and their dynamic perturbation in many aspects is an important mechanism of diabetic kidney disease (DKD). Single-nucleus RNA sequencing (snRNA-seq) technology is a high-throughput sequencing analysis technique for RNA at the level of a single cell nucleus. Here, our DKD mouse kidney single-cell RNA sequencing conveys a more comprehensive mitochondrial profile, which helps us further understand the therapeutic response of this unique organelle family to drugs.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
Department of Applied Computer Science, University of Winnipeg, Winnipeg, MB, R3B 2E9, Canada.
Background: Comprehensively mapping the hierarchical structure of breast cancer protein communities and identifying potential biomarkers from them is a promising way for breast cancer research. Existing approaches are subjective and fail to take information from protein sequences into consideration. Deep learning can automatically learn features from protein sequences and protein-protein interactions for hierarchical clustering.
View Article and Find Full Text PDFMikrochim Acta
January 2025
School of Chemistry and Chemical Engineering, Yantai University, Yantai, 264005, China.
A lanthanide ion-based metal-organic framework (Eu-TATAB nanorods) was designed and synthesized as an effective tri-mode nanoprobe for sensitive and portable detection of ethanol content in a water-ethanol mixture. The assay was based on the responsive properties of Eu-TATAB nanorods to ethanol stimulus and their adaptive encapsulation capability towards optically active lanthanides. With the addition of ethanol to the Eu-TATAB nanorods, the structure was destroyed, resulting in a decrease in luminescence, electrochemiluminescence, and ultraviolet-visible spectrophotometric signals by perturbing energy transfer in the Eu-TATAB nanorods.
View Article and Find Full Text PDFJ Chem Phys
January 2025
Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37830, USA.
The linear scaling divide-expand-consolidate (DEC) framework is expanded to include unrestricted Hartree-Fock references. By partitioning the orbital space and employing local molecular orbitals, the full molecular calculation can be performed as independent calculations on individual fragments, making the method well-suited for massively parallel implementations. This approach also incorporates error control through the fragment optimization threshold (FOT), which maintains precision and consistency throughout the calculations.
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