The ordinary gain score, g, is defined as g = x2-x1, where x1 is the pretest score and x2 is the posttest score. The present study extends and refines previous research on the reliability and validity of gain scores. Using particular values as stated in the tables and graphs, the pre- and posttest reliabilities, pre- and posttest validities, ratios of pretest to posttest standard deviations, and correlations between the pretest and posttest were varied systematically to examine the effects of these parameter configurations on gain scores' reliability and validity. Results plotted graphically provide insight via visual interpretation not easily inferred using only values from a table. One interesting finding was that the reliability of a gain score can be at a maximum when the validity is at a minimum. Another is that a high correlation between pre- and posttest was beneficial to the validity of the gain score but detrimental to its reliability. By identifying the situations in which gain scores can be reliable and valid, findings inform researchers when gain scores should or should not be used.
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http://dx.doi.org/10.2466/03.PMS.111.5.399-406 | DOI Listing |
Quantitative measurements produced by mass spectrometry proteomics experiments offer a direct way to explore the role of proteins in molecular mechanisms. However, analysis of such data is challenging due to the large proportion of missing values. A common strategy to address this issue is to utilize an imputed dataset, which often introduces systematic bias into down-stream analyses if the imputation errors are ignored.
View Article and Find Full Text PDFSchizophr Res Cogn
June 2025
University Department of Child and Adolescent Psychiatry, Children's Hospitals of NICE CHU-Lenval, Nice, France.
Objective: To conduct a systematic review of neurocognitive dysfunctions in patients with childhood-onset schizophrenia (COS), a neuropsychiatric disorder that occurs before age 13 and is rarer and more severe than adult-onset schizophrenia.
Method: A search was made in the PubMed database. Sixty-seven studies (out of 543) which analyzed Intellectual Quotient (IQ), attentional, memory and executive functions were selected by two independent researchers.
Curr Pharm Des
January 2025
Centre of Experimental Medicine and Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.
Introduction: Fungal endophytes have mutualistic associations with the plant's host, communicating through genetic and metabolic processes. As a result, they gain the ability to generate therapeutically effective metabolites and their derivatives.
Methods: The current study aims to assess antioxidant potential along with the identification of robust metabolites within the crude extract of a potent endophytic fungus Xylaria ellisii isolated from leaf tissues of the Acorus calamus Linn plant.
Objective This study explored the physical and mental health status and living conditions of fathers raising 0-year-old multiples in Japan compared with those raising singletons to gain insight into fathers' health issues and the need for support.Methods Household and health data from the Comprehensive Survey of Living Conditions (2016, 2019, and 2022) were used. Because of the small number of fathers with multiples in each dataset, three datasets were combined.
View Article and Find Full Text PDFObjective: To identify and characterize how race and ethnicity influence the relationship between autism and weight status, across all categories of weight from underweight to severe obesity.
Study Design: We developed a propensity score-matched cross-sectional dataset of children with and without parent-reported autism in the National Survey of Children Health (NSCH, 2016-2022) and Adolescent Brain and Cognition Development Study (ABCD, 2016-2018). We included non-Hispanic Asian, non-Hispanic Black, non-Hispanic White, and Hispanic children aged 6 to 17 years.
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