Endoscopic celiac plexus neurolysis (CPN) has become the procedure of choice for the management of patients with pancreatic cancer and abdominal pain unresponsive to medical treatment. It is necessary to differentiate between CPN and endoscopic celiac plexus block performed in patients with benign disease. In this review we describe the technique of this procedure with special emphasis on technical details.
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http://dx.doi.org/10.4253/wjge.v2.i6.228 | DOI Listing |
Objective: To describe a technique for ultrasound-guided celiac plexus block in horses and characterize its effect on intestinal motility in healthy horses.
Methods: This study was conducted from January 2022 through June 2022. In phase 1 (dye study), an ultrasound-guided technique was optimized, and dye deposition around the celiac plexus branches was evaluated via postmortem dissection in 6 horses.
Hematol Oncol Clin North Am
January 2025
Department of Radiation Oncology, University of Miami, Miami, OH, USA.
Functional radiosurgery is a minimally invasive and highly precise approach to managing refractory cancer pain, offering targeted interventions for both nociceptive and neuropathic pain mechanisms. By focusing on key neuroanatomical targets, such as the thalamus, cingulate cortex, pituitary gland, celiac plexus, and dorsal root ganglia, functional radiosurgery provides effective relief for complex pain syndromes that are often unresponsive to conventional therapies. Advances in imaging and treatment delivery have enhanced the safety and efficacy of these techniques, allowing clinicians to tailor interventions to individual patients.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Department of Gastroenterology & Hepatology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Pancreatic cancer is associated with high rates of morbidity and mortality. Endoscopic ultrasound (EUS)-guided biopsy has become the standard diagnostic modality per the guidelines. The use of EUS has been growing for providing various treatments in patients with pancreatic cancers: biliary and gallbladder drainage for those with malignant biliary obstruction, gastroenterostomy for malignant gastric outlet obstruction, celiac plexus/ganglia neurolysis for pain control, radiofrequency ablation, placement of fiducial markers, and injection of local chemotherapeutic agents.
View Article and Find Full Text PDFPract Radiat Oncol
January 2025
Department of Radiation Oncology, Ascension St. Vincent's East, Birmingham, Alabama.
Palliat Med Rep
December 2024
Department of Palliative Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Background: Because of the limitations of pharmacological therapy, nonpharmacological therapies including intervention procedures are also important for quality of cancer pain management.
Objective: To clarify the availability of, number performed, barriers to performing, and educational practices of four interventional procedures (celiac plexus neurolysis/splanchnic nerve neurolysis, phenol saddle block, epidural analgesia, and intrathecal analgesia) in designated cancer hospitals.
Design: Cross-sectional survey.
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