Aim: To present current and new knowledge on congenital self-healing reticulohistiocytosis, a benign variant of cutaneous Langerhans cell histiocytosis presenting with skin lesions in the neonatal period.

Methods: We describe and photo document two cases of this rare disease and review the literature.

Results: Only few newborns have acute access to a neonatal dermatologist, and we demonstrate how the spontaneous cutaneous involution may happen even prior to the first dermatological assessment. As no sole criterion can reliably distinguish the self-healing form from disseminated disease, multidisciplinary assessment and follow-up are essential.

Conclusion: Our data document how easily the diagnosis congenital self-healing reticulocytosis may be missed and emphasize the importance and value of instant clinical photographing at the neonatal unit and the use of teledermatology whenever congenital self-healing reticulohistiocytosis is suspected.

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1651-2227.2010.02123.xDOI Listing

Publication Analysis

Top Keywords

congenital self-healing
16
self-healing reticulohistiocytosis
12
congenital
4
reticulohistiocytosis diagnostic
4
diagnostic challenge
4
challenge aim
4
aim current
4
current knowledge
4
knowledge congenital
4
self-healing
4

Similar Publications

Bone defects can arise from trauma or pathological factors, resulting in compromised bone integrity and the loss or absence of bone tissue. As we are all aware, repairing bone defects is a core problem in bone tissue engineering. While minor bone defects can self-repair if the periosteum remains intact and normal osteogenesis occurs, significant defects or conditions such as congenital osteogenesis imperfecta present substantial challenges to self-healing.

View Article and Find Full Text PDF
Article Synopsis
  • * The exact causes of LCH are not well understood, but they may involve genetic factors, immune system issues, and environmental influences during pregnancy.
  • * This report discusses a case of a newborn girl with LCH whose mother had a varicella-zoster infection during pregnancy, hinting at a potential link between prenatal factors and the condition.
View Article and Find Full Text PDF

Recent advances of chitosan-based composite hydrogel materials in application of bone tissue engineering.

Heliyon

October 2024

Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, National Center for Orthopaedic Medicine, Shanghai, 200233, China.

Article Synopsis
  • Bone defects from trauma, tumors, infections, and congenital conditions are major orthopedic challenges, complicated by factors like aging and preexisting conditions that can hinder the body's ability to repair itself.
  • Traditional bone repair methods, such as autografts and allografts, are effective but come with limitations, including the need for additional surgeries and potential complications.
  • Chitosan (CS), a biocompatible and biodegradable material, shows great promise for bone repair due to its ability to promote bone regeneration, density, and fracture healing, suggesting innovative approaches for future research in this field.
View Article and Find Full Text PDF

A Case of Spontaneous Recovery in an Infant with Nail Candidiasis Probably Related to Nail Trauma During Vaginal Delivery.

Infect Drug Resist

July 2024

Department of Dermatology and Laboratory of Medical Mycology, Jining No. 1 People's Hospital, Jining, Shandong, People's Republic of China.

Onychomycosis in infants is a rare fungal infection. The condition is frequently linked to congenital or secondary immunodeficiency, as well as exposure to contaminated environments. In this report, we present a case of infant onychomycosis, likely infected during birth delivery from the mother with vaginal candidiasis.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!