Toxoplasma gondii is widely distributed in humans and other animals, including wild rats throughout the world, but little is known of the prevalence of T. gondii in rats in China. The seroprevalence of T. gondii in rats ( Rattus norvegicus and Rattus flavipectus ) was investigated in Guangzhou, southern China, between November 2009 and January 2010. In total, 217 rat serum samples were collected; antibodies to T. gondii were detected by the modified agglutination test (MAT), and 7 (3.2%) were found positive (titers ≥ 1:40). The seroprevalence was higher (3.4%) in R. norvegicus than in R. flavipectus (3.0%), but the difference was not statistically significant (P > 0.05). All 7 positive rats were female; no T. gondii antibodies were detected in males. This is the first extensive survey of T. gondii infection in rats in southern China, and the results have public health implications in this region.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1645/GE-2610.1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of Experimental Congenital Toxoplasmosis on the Thyroid Gland: Histopathological and Immunobiochemical Indices Assessment.
Acta Parasitol
January 2025
Department of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Purpose: The thyroid gland is one of the most vital endocrine organs. It is responsible for the synthesis and secretion of hormones principally triiodothyronine (T3) and thyroxine (T4). These hormones play a significant role in the functions and the metabolism of the body.
View Article and Find Full Text PDFToxoplasma gondii Infection in the Male Reproductive System: A Systematic Review.
Acta Parasitol
January 2025
Reproduction Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia- UdeA, Medellín, Antioquia, Colombia.
Purpose: Toxoplasmosis is a worldwide widespread parasitic infection; it affects about 30% of the global population, either through acute toxoplasmosis or its sequels. Even though the male reproductive system is not the primary target for Toxoplasma gondii (T. gondii), studies have inquired into the possibility of presenting repercussions in this system directly or indirectly due to toxoplasmosis.
View Article and Find Full Text PDFEffects of diet and ovariectomy on brain infection: functional alterations and neuronal loss in rats.
Brain Commun
December 2024
Brain Research Africa Initiative (BRAIN), P.O. Box 25625, Yaoundé, Cameroon.
Epidemiological evidence associates latent infection with the development of neuropsychiatric disorders, and various immunological and environmental factors play key pathophysiological roles through host immune response alterations. We investigated the cognitive and motor alterations occurring in the terminal stage of infection in rats, and whether a low-protein diet, a high-fat diet or ovariectomy may accelerate their development, given the role of malnutrition and menopause on immunity and resistance to infection. In two sets of experiments, 2-month-old (157.
View Article and Find Full Text PDFThe degree of toxoplasmosis and testicular histomorphometry in rats.
Sci Rep
November 2024
Department of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Toxoplasma gondii (T. gondii) ranks as the third most common parasitic parasite worldwide, and it is estimated that > 60% of the population is infected with T. gondii worldwide at some point in their lives.
View Article and Find Full Text PDFEvaluation of protective efficacy of recombinant Toxoplasma gondii DDX39 protein vaccine against acute and chronic T. gondii infection in mice.
Acta Trop
December 2024
Xinxiang Key Laboratory of Pathogenic Biology, Department of Pathogenic Biology, School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, China. Electronic address:
Toxoplasma gondii, a pervasive parasite responsible for toxoplasmosis, poses significant health risks to humans and animals. In this study, we investigated the immunogenicity and protective efficacy of the recombinant T. gondii DDX39 protein formulated with ISA201 adjuvant (rTgDDX39) as a candidate vaccine against toxoplasmosis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!