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Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review.
Pharmaceutics
January 2025
Division of Clinical Pharmacology, Department of Medicine, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA.
Long-acting and extended-release drug delivery strategies have greatly improved treatment for a variety of medical conditions. Special populations, specifically infants, children, young people, and pregnant and postpartum women, could greatly benefit from access to these strategies but are often excluded from clinical trials. We conducted a systematic review of all clinical studies involving the use of a long-acting intramuscular injection or implant in infants, children, young people, and pregnant and postpartum people.
View Article and Find Full Text PDFBibliometric analysis of teen pregnancy research in Asia-Africa: Explore the future scope.
J Educ Health Promot
December 2024
Research Center for Public Health and Nutrition, National Research and Innovation Agency, Jakarta, Indonesia.
Background: Adolescent pregnancy is prevalent in Asian-African countries. Hence, it is critical to track the progress of research and development trends related to the topic. The study aimed to characterize published articles on teen pregnancy by measuring the authors' country and affiliation, most relevant and cited journals, thematic research, and growth trends.
View Article and Find Full Text PDFFactors associated with adolescent pregnancy among girls aged between 15 and 19 years in Muhanga district, Rwanda.
BMC Public Health
January 2025
Department of Public Health, Mount Kenya University, Kigali, Rwanda.
Background: Adolescent pregnancy, also known as teenage pregnancy, is an unwanted pregnancy affecting girls aged 15-19 years. With a global prevalence of 25%, Africa has 18.8% of female adolescents become pregnant, preventing them from a better standard of living, such as good education and parental care, and adolescent pregnancy, which poses health risks, educational and career disruptions, financial strain, and lower academic achievement, while also increasing public costs and social service demand.
View Article and Find Full Text PDFCorrelates of maternal health services utilization among adolescent mothers in Ghana: analysis of Ghana maternal health survey 2017.
BMC Pregnancy Childbirth
January 2025
Regional Institute for Population Studies, University of Ghana, Legon-Accra, Ghana.
Background: The prevalence of adolescent pregnancy is high in developing countries and poses a public health threat. This study aimed to assess the coverage and correlates of optimal ANC visits, early initiation of ANC visits, assisted delivery and health facility delivery among adolescent mothers.
Methods: We analysed data from the 2017 Ghana Maternal Health Survey (GMHS), using a sample of 567 (weighted) and 527 (unweighted) adolescent mothers with at least one live birth or stillbirth in the five (5) years preceding the survey.
Epigenome-wide association study of objectively measured physical activity in peripheral blood leukocytes.
BMC Genomics
January 2025
Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.
Background: Few studies have explored the association between DNA methylation and physical activity. The aim of this study was to evaluate the association of objectively measured hours of sedentary behavior (SB) and moderate physical activity (MPA) with DNA methylation. We further aimed to explore the association between SB or MPA related CpG sites and cardiometabolic traits, gene expression, and genetic variation.
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