Two patients, one of whom was pregnant, developed superior vena caval thrombosis while receiving central parenteral nutrition. They were successfully treated with recombinant tissue plasminogen activator (t-PA).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426832PMC
http://dx.doi.org/10.1136/pgmj.66.775.398DOI Listing

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