Eosinophilic fasciitis: a rare skin sclerosis.

Patholog Res Int

Service d'Anatomie et Cytologie Pathologiques, Hôpital Ambroise Paré, AP-HP, Université de Versailles Saint-Quentin-en-Yvelines, 9 Avenue Charles de Gaulle, 92104 Boulogne-Billancourt Cedex, France.

Published: December 2010

Eosinophilic fasciitis (Schulman's syndrome) is a rare disease with specific clinical symptoms such as the groove sign which facilitate diagnosis. We report a typical case of eosinophilic fasciitis in an otherwise healthy 49-year-old man who presented with "prayer and groove signs". Histological analysis showed sclerosis and eosinophilic infiltration of the fascia. The patient was successfully treated with systemic corticotherapy and Cyclosporine. A short review of the clinicopathological features of the lesions is presented.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995928PMC
http://dx.doi.org/10.4061/2011/716935DOI Listing

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