Mycobacterium ulcerans infection is responsible for severe skin lesions in sub-Saharan Africa. We enrolled 30 Beninese patients with Buruli ulcers in a pilot study to evaluate efficacy of an oral chemotherapy using rifampicin plus clarithromycin during an 8-week period. The treatment was well tolerated, and all patients were healed by 12 months after initiation of therapy without relapse.
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Article Synopsis
- Buruli ulcer (BU) is a neglected tropical disease caused by the bacterium Mycobacterium ulcerans, primarily affecting skin and subcutaneous tissue, with transmission dynamics varying by geographic area, particularly in endemic regions like Victoria, Australia.
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