Background: the uptake of influenza vaccination represents a simple marker of proactive care of older people. However, many still do not receive the vaccine. To understand this challenge better, we investigated the relationship between patient characteristics (demographic, physical and psychological health and health service use) and vaccination uptake in a sample of community-dwelling older people in two adjacent but differently structured healthcare systems (Northern Ireland (NI) and the Republic of Ireland (RoI)).
Methods: a total of 2,033 randomly selected community-dwelling older adults (65 years and older) were interviewed in their homes.
Results: rates of uptake were 78% in NI and 72% in RoI. The uptake was greater with older age (odds ratio (OR) 1.6, 95% confidence interval (CI) = 1.3-2.1, P < 0.0005), widowhood (OR = 1.5, 95% CI = 1.1-2.3, P = 0.02), living in NI (OR = 0.77, 95% CI = 0.6-0.9, P = 0.04), greater functional impairment (OR RoI 2.0, 95% CI = 0.8-3.5, P = 0.03), more frequent use of family doctor (OR RoI 0.5, 95% CI = 0.3-0.6, P = 0.0001; NI 0.6, 95% CI = 0.4-0.9, P = 0.01) and greater use of services such as chiropody (OR NI 0.6, 95% CI = 0.4-0.9, P = 0.01), meals-on-wheels (OR RoI 1.3, 95% CI = 0.4-2.2, P = 0.03), social work (OR RoI 1.2, 95% CI = 0.3-1.9, P = 0.05) and occupational therapy (OR RoI 1.3, 95% CI = 0.5-2.5, P = 0.02).
Conclusion: the uptake rates in both healthcare systems exceeded targets. Higher rates of vaccination were found among older people, those who were married and those who made greater use of hospital and community services. Increased exposure to health services may enhance trust in health care leading to higher vaccination uptake.
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http://dx.doi.org/10.1093/ageing/afq152 | DOI Listing |
Objectives: The pairing of immunotherapy and radiotherapy in the treatment of locally advanced nonsmall cell lung cancer (NSCLC) has shown promise. By combining radiotherapy with immunotherapy, the synergistic effects of these modalities not only bolster antitumor efficacy but also exacerbate lung injury. Consequently, developing a model capable of accurately predicting radiotherapy- and immunotherapy-related pneumonitis in lung cancer patients is a pressing need.
View Article and Find Full Text PDFBMC Cancer
January 2025
Department of Urology, Fujian Union Hospital, Fujian Medical University, Fuzhou, 350001, Fujian Province, China.
Background: Prostate cancer (PCa) is definitively diagnosed by systematic prostate biopsy (SBx) with 13 cores. This method, however, can increase the risk of urinary retention, infection and bleeding due to the excessive number of biopsy cores.
Methods: We retrospectively analyzed 622 patients who underwent SBx with prostate multiparametric MRI (mpMRI) from two centers between January 2014 to June 2022.
AJNR Am J Neuroradiol
January 2025
From the Department of Neurology, the First Hospital of Jilin University, Changchun, Jilin Province, China.
Background And Purpose: Differentiating Parkinson's Disease (PD) from Atypical Parkinsonism Syndrome (APS), including Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP), is challenging, and there is no gold standard. Integrating quantitative susceptibility mapping (QSM) and morphometry can help differentiate PD from APS and improve the internal diagnosis of APS.
Materials And Methods: In this retrospective study, we enrolled 55 patients with PD, 17 with MSA-parkinsonian type (MSA-P), 15 with MSA-cerebellar type (MSA-C), and 14 with PSP.
Transl Cancer Res
December 2024
Department of Stomatology, The First Hospital of Lanzhou University, Lanzhou, China.
Background: The rising incidence of parotid gland tumors, with a focus on pleomorphic adenomas (PMA) and Warthin tumors (WT), necessitates accurate preoperative distinction due to their treatment variability and PMA's malignant potential. Traditional imaging, while valuable, has limited accuracy. This study employs multi-slice computed tomography (MSCT) radiomics coupled with serum alpha-L-fucosidase (AFU) levels to develop a diagnostic model aimed at elevating clinical discernment and precision therapy delivery.
View Article and Find Full Text PDFBMC Med Imaging
January 2025
Cancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, No. 158 Shang tang Road, Hangzhou, Zhejiang, 310011, China.
Background: This study aims to evaluate the predictive usefulness of a habitat radiomics model based on ultrasound images for anticipating lateral neck lymph node metastasis (LLNM) in differentiated thyroid cancer (DTC), and for pinpointing high-risk habitat regions and significant radiomics traits.
Methods: A group of 214 patients diagnosed with differentiated thyroid carcinoma (DTC) between August 2021 and August 2023 were included, consisting of 107 patients with confirmed postoperative lateral lymph node metastasis (LLNM) and 107 patients without metastasis or lateral cervical lymph node involvement. An additional cohort of 43 patients was recruited to serve as an independent external testing group for this study.
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