Peptide deformylase (PDF), which removes the formyl group at the N-terminal methionine residue of nascent protein, has been recognized as a potent target for antibacterial therapy. We report herein the synthesis and structure-activity relationship studies of non-peptide PDF inhibitors.
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| http://dx.doi.org/10.1016/j.bmcl.2010.11.056 | DOI Listing |
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