AI Article Synopsis
- The study aimed to assess the mid-sagittal areas of the vermis and posterior fossa in fetuses with different Dandy-Walker variants compared to normal controls.
- Researchers analyzed MR images of 25 fetuses diagnosed with Dandy-Walker complex and 85 control fetuses, measuring and statistically comparing the areas for significant differences.
- The findings suggested that fetuses with Dandy-Walker variants (specifically HVR and HV) had smaller vermis areas and larger posterior fossa areas compared to control subjects, providing insights into the anomalies present in these conditions.
Article Abstract
Objective: To measure the mid-sagittal areas of vermis (VA) and of posterior fossa (PFA) and determine their differences among fetuses with various Dandy-Walker (DW) entities and control subjects.
Methods: We reviewed data in 25 fetal patients with a MR diagnosis of DW complex including hypoplastic vermis (HV), HV with rotation (HVR), and mega cistern magna (MCM), and in 85 fetal controls with normal CNS. PFA and VA of each subject were manually traced on mid-sagittal MR images. Regarding each of VA and PFA, after age correction, we determined statistically significant differences among HVR, HV, MCM, and control groups.
Results: The mean VA residue of MCM was greater than that of the control, which was in turn greater than those of HVR and HV. The mean PF residue of the control was smaller than all other groups.
Conclusion: Fetuses with HVR or HV had smaller VA than fetuses with MCM or control subjects. Fetuses with MCM, HVR, or HV had larger PFA than control subjects. These results may be an early step leading to better understanding of the confusion about the PF anomalies in future.
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| http://dx.doi.org/10.1016/j.ejrad.2010.11.003 | DOI Listing |
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