AI Article Synopsis

  • A. phagocytophilum is a tick-borne pathogen responsible for human granulocytic anaplasmosis, raising public health concerns as an emerging infectious disease.
  • Researchers in Hokkaido, Japan, found this pathogen in 7.1% of field-collected Ixodes persulcatus ticks and 3.4% of cattle tested.
  • Future studies are needed to explore the effects of A. phagocytophilum infection to better understand its impact on domestic animals.

Article Abstract

The tick-borne pathogen, Anaplasma phagocytophilum (A. phagocytophilum), the causative agent of human granulocytic anaplasmosis (HGA), is increasingly becoming a public health concern as an aetiological agent for emerging infectious disease. We found A. phagocytophilum infection in a pooled sample of field-collected Ixodes persulcatus (I. persulcatus) ticks from one district in Hokkaido, Japan. Thus, to further investigate the prevalence in field-collected ticks, we used PCR assays targeting the A. phagocytophilum gene encoding 44 kDa major outer membrane protein (p44) for screening of I. persulcatus ticks and samples from cattle from pastures. Out of the 281 I. persulcatus ticks, 20 (7.1%) were found to harbor A. phagocytophilum DNA. The infection rate for A. phagocytophilum in cattle was 3.4% (42/1251). In future studies, it will be necessary to investigate effects of the infection in order to understand its pathogenesis of A. phagocytophilum in domestic animals.

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Source
http://dx.doi.org/10.1016/j.vetmic.2010.11.025DOI Listing

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