Background: The breast reconstruction is an integral part of the treatment for breast cancer after mastectomy. A lot of methods were described like the free TRAM flap reconstruction. The technical difficulty, the length of the procedure and the post-operative monitoring of this reconstruction make it as an alternative used generally in a hospital setting.
Purpose: The goal of this retrospective study is to document the validity of this technique in the private practice setting.
Patients And Method: Between 2003 and 2006, 20 patients were operated on for a breast reconstruction using a free TRAM flap by a double "melting-pot" surgical team in a private clinic in Tunisia. The average age was 43 years and the average delay for the breast reconstruction was 16 months after mastectomy. We have always used the same surgical technique: a free TRAM flap plugged on the internal mammary vessels. The arterial anastomosis was stitched by a thread and the venous anastomosis was done by using a microvascular anastomotic coupler. The average operating time was 4 hours. The average stay in the clinic was 5 days.
Results: There was no total flap loss. We observed one partial necrosis that healed in 5 weeks with dressings, one hematoma that required a surgical evacuation at the second day and one case of abdominal wall weakness treated by a mesh repair at one year.
Conclusion: The breast reconstruction using a free TRAM flap is a reliable and safe technique that can be used without any difficulties in a private practice setting if it is made by a surgical team familiar with microsurgery and respecting its criteria with also a good management and strategy for aftercare.
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http://dx.doi.org/10.1016/j.anplas.2009.11.010 | DOI Listing |
J Surg Oncol
December 2024
Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
J Transl Med
November 2024
Department of Orthopaedic Surgery, Stanford University, 450 Broadway Street, Redwood City, CA, 94025, USA.
Introduction: Diagnosing infected joint replacements relies heavily on assessing the neutrophil response to bacteria. Bacteria form biofilms on joint replacements. Biofilms are sessile bacterial communities encased in a protective extracellular matrix, making them notoriously difficult to culture, remarkably tolerant to antibiotics, and able to evade phagocytosis.
View Article and Find Full Text PDFOncologist
November 2024
Real World Evidence Solutions, CONEXTS, Novartis Ireland Ltd., Dublin 4, D04 NN12, Ireland.
Background: In BRAF-mutated high-risk melanoma, targeted therapy (BRAF/MEK inhibitors) and checkpoint inhibitor (CPI) immunotherapy have durable benefits as first-line (1L) adjuvant therapy. Based on differing action mechanisms of BRAF/MEK inhibitors and CPI immunotherapies, there is interest in evaluating the activity of 2L adjuvant targeted therapy in decreasing the risk of subsequent recurrence after repeat resection following relapse on/after 1L adjuvant CPI.
Patients And Methods: This was a retrospective review of BRAF V600-mutated resected stage III/IV melanoma patients in the United States, Australia, and The Netherlands who received 1L adjuvant CPI immunotherapy, relapsed locoregionally/distantly, were again resected to no evidence of disease, and received dabrafenib/trametinib (dab/tram) as 2L adjuvant therapy.
Plast Reconstr Surg Glob Open
August 2024
From the Division of Plastic and Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Background: The gold standard of microsurgical breast reconstruction is the deep inferior epigastric perforator (DIEP) free flap. As techniques have evolved, DIEP flaps have significantly reduced the morbidity previously caused by transverse rectus abdominis muscle (TRAM) and muscle-sparing TRAM flaps. However, abdominal wall complications continue to persist after DIEP flap surgery, with bulge rates reported as high as 33%.
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
October 2024
Division of Plastic Surgery, Department of Surgery, Queen's University, Kingston, ON, Canada.
3D-printed vascular models can enhance flap harvesting efficiency in abdominal free flap breast reconstruction, reducing the use of operating room time. However, no economic analyses with respect to model use in this context have been conducted to date. As such, this study examines model cost-benefit tradeoffs for use in abdominal free flap breast reconstruction.
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