Background: Periphpral ulcerative keratitis (PUK) is a disorder consisting of a crescent-shaped destructive inflammation of the perilimbal corneal stroma.
Case: We present a case of PUK following acute bacterial conjunctivitis in a 60-year-old lady with a history of on-and-off joint pain for two years. After admission to the hospital, she underwent conjunctival resection and was given topical and oral steroids. She was prescribed hydroxychloroquine after confirming the diagnosis of rheumatoid arthritis with a positive RA factor.
Conclusion: This report highlights the role of infection as a triggeringagent in the induction of PUK in an otherwise quiescent cornea.
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http://dx.doi.org/10.3126/nepjoph.v2i1.3709 | DOI Listing |
BMC Ophthalmol
January 2025
Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
Background: Fungal keratitis can develop after plant injury or after prolonged glucocorticoid use. Typical manifestations include corneal infiltrates, satellite lesions, plaques, and an immune ring. Some cases exhibit atypical signs, requiring reliance on etiological examination.
View Article and Find Full Text PDFAm J Ophthalmol
January 2025
the Wilmer Eye Institute, the Department of Ophthalmology, the Johns Hopkins University School of Medicine, Baltimore, MD, USA; the Department of Epidemiology, the Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address:
Purpose: To evaluate clinical and treatment outcomes in patients with peripheral ulcerative keratitis (PUK).
Design: Retrospective, case series SUBJECTS: Patients diagnosed with PUK at the Wilmer Eye Institute between January 2003 and October 2022.
Methods: Data collected included demographics, presence of systemic disease, disease laterality, duration of disease, PUK activity, presence of corneal perforation, and treatments.
Sci Rep
January 2025
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Corneal ulcer is one of the most important ophthalmic emergencies. A portable, recordable, and smartphone-attachable slit-lamp device called the "Smart Eye Camera" (SEC) is introduced to compare evaluating corneal ulcers between the SEC and the conventional slit-lamp. A total of 110 participants were included in the study, consisting of 55 patients with corneal ulcers and 55 age- and gender-matched healthy volunteers as controls.
View Article and Find Full Text PDFJ Community Hosp Intern Med Perspect
November 2024
Medstar Health Internal Medicine Residency Program, Baltimore, MD, USA.
The co-occurrence of inflammatory eye disease and hidradenitis suppurativa (HS) is uncommon; ocular involvement typically manifests as anterior uveitis. In this report, we present a unique case of peripheral ulcerative keratitis (PUK) where both infectious and rheumatological workup was negative, leading us to consider the possibility of an association between this condition and severe HS. As far as we are aware, there have only been six documented cases of PUK associated with HS.
View Article and Find Full Text PDFCornea
January 2025
Department of Ophthalmology, Stanford University, Byers Eye Institute, Palo Alto, CA.
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