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Plasma treatment is associated with decreased brain lesion and resuscitation requirements after traumatic brain injury in a swine model of prolonged damage-control resuscitation.
J Trauma Acute Care Surg
October 2024
From the Department of Surgery, Northwestern Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Background: Hemorrhage and traumatic brain injury (TBI) are the leading causes of death in trauma. Future military conflicts are likely to be in austere environments, where prolonged damage-control resuscitation (p-DCR) may be required for 72 hours before evacuation. Previous studies showed that early administration of fresh frozen plasma (FFP) during p-DCR can significantly decrease the volume of resuscitation required in models of hemorrhagic shock and also provide neuroprotection after TBI.
View Article and Find Full Text PDFPhysical Demands of Brazilian Air Force Critical Combat Tasks.
Mil Med
December 2024
School of Physical Education-FEF/UNICAMP, State University of Campinas, Campinas, SP 13083-970, Brazil.
Introduction: The present study aimed to identify the physical demands of Brazilian Air Force (BAF) critical Combat Tasks (CTs) and investigate the occurrence of differences in their difficulty perceived ratings, considering aspects such as sex, military experience, and academic degree of the evaluators.
Methods: The Subject Matter Expert (SME) cohort was assembled based on the BAF's Physical Training Specialists (n = 13, military, at least 2 years of experience). Based on the BAF's previous studies, a questionnaire defining and rating the physical demands of 12 BAF critical CTs was developed.
Tactical Combat Casualty Care (TCCC) has been designated by the U.S. Department of Defense as the military standard for battlefield trauma care.
View Article and Find Full Text PDFDevelopment of Naphthalene-Derivative Bis-QACs as Potent Antimicrobials: Unraveling Structure-Activity Relationship and Microbiological Properties.
Molecules
November 2024
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, 119991 Moscow, Russia.
While the pandemic is behind us, the world community faces a global threat of bacterial resistance outbreak. One of the key ways to combat the spread of multi-resistant bacteria is infection prevention and control tactics using modern antiseptic and disinfectant compositions. Herein, we continue the path to unravel the structure-activity relationship (SAR) of potent pyridine-derived biocide class bis-quaternary ammonium compounds (QACs).
View Article and Find Full Text PDFBackground: Research indicates that number of nurse practitioners (NPs) is growing. Additional training is necessary to increase self-efficacy in tactical settings. Evidence shows the Tactical Combat Casualty Care (TC3) course is the national standard for tactical medical training.
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