Palladium-catalyzed direct and regioselective C-H bond functionalization/oxidative acetoxylation of indoles.

J Org Chem

State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

Published: January 2011

The first general examples of palladium-catalyzed direct and selective oxidative C3-acetoxylation of indoles are presented. The mild reaction conditions (70 °C and with weak base, KOAc) in this indole C-H-acetoxylation are notable.

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Source
http://dx.doi.org/10.1021/jo101584kDOI Listing

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